N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

C308H362Cl5F14N101O34 — CID 167566271

IUPACN-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1
InChIInChI=1S/2C28H35F2N9O2.3C27H35N9O3.2C26H30F2N8O3.2C25H29ClN8O3.3C23H23ClF2N8O3/c2*1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-17(37)30-23-12-18(7-8-28-23)39-19-11-21-25(29-14-19)32-26(35(21)6)31-24-13-22(27(2,3)4)36(33-24)16-20-15-34(5)9-10-38-20;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;2*1-14(35)29-19-10-16(6-8-27-19)37-17-12-28-23-22(21(17)26)33(5)24(31-23)30-20-11-18(25(2,3)4)34(32-20)15-7-9-36-13-15;3*1-12(35)29-17-8-14(4-6-27-17)37-15-10-28-21-20(19(15)24)33(3)22(31-21)30-18-9-16(23(2,25)26)34(32-18)13-5-7-36-11-13/h2*7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7-8,11-14,20H,9-10,15-16H2,1-6H3,(H,28,30,37)(H,29,31,32,33);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15H,7,9,13H2,1-5H3,(H,27,29,35)(H,28,30,31,32);3*4,6,8-10,13H,5,7,11H2,1-3H3,(H,27,29,35)(H,28,30,31,32)/t18-;;2*20-;;15-;;2*15-;2*13-;/m0.10.1.1010./s1
InChIKeyFIDPLMWETVSUCI-UHLBIFMHSA-N
MW6466.19 g/mol
LogP55.70
Rot. Bonds82

About N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (PubChem CID 167566271) has the molecular formula C308H362Cl5F14N101O34 and a molecular weight of 6466.19 g/mol. Its IUPAC name is N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.

Molecular Properties

Compound NameN-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
PubChem CID167566271
Molecular FormulaC308H362Cl5F14N101O34
Molecular Weight6466.19 g/mol
Exact Mass6459.79
IUPAC NameN-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1
InChIInChI=1S/2C28H35F2N9O2.3C27H35N9O3.2C26H30F2N8O3.2C25H29ClN8O3.3C23H23ClF2N8O3/c2*1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-17(37)30-23-12-18(7-8-28-23)39-19-11-21-25(29-14-19)32-26(35(21)6)31-24-13-22(27(2,3)4)36(33-24)16-20-15-34(5)9-10-38-20;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;2*1-14(35)29-19-10-16(6-8-27-19)37-17-12-28-23-22(21(17)26)33(5)24(31-23)30-20-11-18(25(2,3)4)34(32-20)15-7-9-36-13-15;3*1-12(35)29-17-8-14(4-6-27-17)37-15-10-28-21-20(19(15)24)33(3)22(31-21)30-18-9-16(23(2,25)26)34(32-18)13-5-7-36-11-13/h2*7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7-8,11-14,20H,9-10,15-16H2,1-6H3,(H,28,30,37)(H,29,31,32,33);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15H,7,9,13H2,1-5H3,(H,27,29,35)(H,28,30,31,32);3*4,6,8-10,13H,5,7,11H2,1-3H3,(H,27,29,35)(H,28,30,31,32)/t18-;;2*20-;;15-;;2*15-;2*13-;/m0.10.1.1010./s1
InChIKeyFIDPLMWETVSUCI-UHLBIFMHSA-N
XLogP55.70
TPSA1449.86 Ų
H-Bond Donors24
H-Bond Acceptors123
Rotatable Bonds82
Heavy Atoms462
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5006466.19
LogP ≤ 555.70
H-Bond Donors ≤ 524
H-Bond Acceptors ≤ 10123

Analyze N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The IUPAC name of N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (CID 167566271) is N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.
What is the SMILES notation for N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The canonical SMILES for N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(CC5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CN(C)CCO5)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(F)F)n([C@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.
What is the InChIKey of N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The InChIKey is FIDPLMWETVSUCI-UHLBIFMHSA-N. The full InChI is InChI=1S/2C28H35F2N9O2.3C27H35N9O3.2C26H30F2N8O3.2C25H29ClN8O3.3C23H23ClF2N8O3/c2*1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-17(37)30-23-12-18(7-8-28-23)39-19-11-21-25(29-14-19)32-26(35(21)6)31-24-13-22(27(2,3)4)36(33-24)16-20-15-34(5)9-10-38-20;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;2*1-14(35)29-19-10-16(6-8-27-19)37-17-12-28-23-22(21(17)26)33(5)24(31-23)30-20-11-18(25(2,3)4)34(32-20)15-7-9-36-13-15;3*1-12(35)29-17-8-14(4-6-27-17)37-15-10-28-21-20(19(15)24)33(3)22(31-21)30-18-9-16(23(2,25)26)34(32-18)13-5-7-36-11-13/h2*7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7-8,11-14,20H,9-10,15-16H2,1-6H3,(H,28,30,37)(H,29,31,32,33);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15H,7,9,13H2,1-5H3,(H,27,29,35)(H,28,30,31,32);3*4,6,8-10,13H,5,7,11H2,1-3H3,(H,27,29,35)(H,28,30,31,32)/t18-;;2*20-;;15-;;2*15-;2*13-;/m0.10.1.1010./s1.
What are the key properties of N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide has a molecular weight of 6466.19 g/mol, XLogP of 55.70, 82 rotatable bonds, 24 hydrogen bond donors, and 123 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-[[5-tert-butyl-1-[(3,3-difluoro-1-methylpiperidin-4-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(4S)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2R)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[[(2S)-4-methylmorpholin-2-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(4-methylmorpholin-2-yl)methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-chloro-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(1,1-difluoroethyl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is sourced from PubChem (CID 167566271), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).