N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

C261H289Cl3F19N83O29 — CID 167699175

IUPACN-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.Cn1c(Nc2nn(C3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(Cl)c3n2C)nn1[C@H]1CCOC1
InChIInChI=1S/C28H35F2N9O2.3C27H31FN8O3.C27H31N9O3.2C26H30F2N8O3.C25H26ClN9O3.2C24H22ClF5N8O3/c1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-27(2,3)22-21(28)24(34-36(22)16-8-10-38-14-16)33-26-32-23-19(35(26)4)11-18(13-30-23)39-17-7-9-29-20(12-17)31-25(37)15-5-6-15;1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;1-14(36)30-19-10-16(6-8-28-19)38-17-12-29-23-22(21(17)26)34(5)24(32-23)31-20-11-18(25(2,3)27-4)35(33-20)15-7-9-37-13-15;2*1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7,9,11-13,15-16H,5-6,8,10,14H2,1-4H3,(H,29,31,37)(H,30,32,33,34);8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);6,8,10-12,15H,7,9,13H2,1-3,5H3,(H,28,30,36)(H,29,31,32,33);2*4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t18-;2*16-;;;15-;;15-;;/m110..0.0../s1
InChIKeyYCVKLRHRPVBGJU-MDDMKNRCSA-N
MW5520.06 g/mol
LogP50.94
Rot. Bonds73

About N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (PubChem CID 167699175) has the molecular formula C261H289Cl3F19N83O29 and a molecular weight of 5520.06 g/mol. Its IUPAC name is N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.

Molecular Properties

Compound NameN-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
PubChem CID167699175
Molecular FormulaC261H289Cl3F19N83O29
Molecular Weight5520.06 g/mol
Exact Mass5515.25
IUPAC NameN-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.Cn1c(Nc2nn(C3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(Cl)c3n2C)nn1[C@H]1CCOC1
InChIInChI=1S/C28H35F2N9O2.3C27H31FN8O3.C27H31N9O3.2C26H30F2N8O3.C25H26ClN9O3.2C24H22ClF5N8O3/c1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-27(2,3)22-21(28)24(34-36(22)16-8-10-38-14-16)33-26-32-23-19(35(26)4)11-18(13-30-23)39-17-7-9-29-20(12-17)31-25(37)15-5-6-15;1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;1-14(36)30-19-10-16(6-8-28-19)38-17-12-29-23-22(21(17)26)34(5)24(32-23)31-20-11-18(25(2,3)27-4)35(33-20)15-7-9-37-13-15;2*1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7,9,11-13,15-16H,5-6,8,10,14H2,1-4H3,(H,29,31,37)(H,30,32,33,34);8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);6,8,10-12,15H,7,9,13H2,1-3,5H3,(H,28,30,36)(H,29,31,32,33);2*4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t18-;2*16-;;;15-;;15-;;/m110..0.0../s1
InChIKeyYCVKLRHRPVBGJU-MDDMKNRCSA-N
XLogP50.94
TPSA1212.83 Ų
H-Bond Donors20
H-Bond Acceptors100
Rotatable Bonds73
Heavy Atoms395
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005520.06
LogP ≤ 550.94
H-Bond Donors ≤ 520
H-Bond Acceptors ≤ 10100

Analyze N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The IUPAC name of N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (CID 167699175) is N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.
What is the SMILES notation for N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The canonical SMILES for N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C5CCOC5)n4)n(C)c3c2C(F)F)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n(C[C@H]5CCN(C)CC5(F)F)n4)n(C)c3c2)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C)n([C@H]5CCOC5)n4)n(C)c3c2C(F)F)ccn1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.Cn1c(Nc2nn(C3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.Cn1c(Nc2nn([C@H]3CCOC3)c(C(C)(C)C)c2F)nc2ncc(Oc3ccnc(NC(=O)C4CC4)c3)cc21.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(Cl)c3n2C)nn1[C@H]1CCOC1.
What is the InChIKey of N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The InChIKey is YCVKLRHRPVBGJU-MDDMKNRCSA-N. The full InChI is InChI=1S/C28H35F2N9O2.3C27H31FN8O3.C27H31N9O3.2C26H30F2N8O3.C25H26ClN9O3.2C24H22ClF5N8O3/c1-17(40)33-23-12-19(7-9-31-23)41-20-11-21-25(32-14-20)35-26(38(21)6)34-24-13-22(27(2,3)4)39(36-24)15-18-8-10-37(5)16-28(18,29)30;3*1-27(2,3)22-21(28)24(34-36(22)16-8-10-38-14-16)33-26-32-23-19(35(26)4)11-18(13-30-23)39-17-7-9-29-20(12-17)31-25(37)15-5-6-15;1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;2*1-14(37)31-19-10-16(6-8-29-19)39-17-12-30-24-22(21(17)23(27)28)35(5)25(33-24)32-20-11-18(26(2,3)4)36(34-20)15-7-9-38-13-15;1-14(36)30-19-10-16(6-8-28-19)38-17-12-29-23-22(21(17)26)34(5)24(32-23)31-20-11-18(25(2,3)27-4)35(33-20)15-7-9-37-13-15;2*1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h7,9,11-14,18H,8,10,15-16H2,1-6H3,(H,31,33,40)(H,32,34,35,36);3*7,9,11-13,15-16H,5-6,8,10,14H2,1-4H3,(H,29,31,37)(H,30,32,33,34);8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-5H3,(H,29,31,37)(H,30,32,33,34);6,8,10-12,15H,7,9,13H2,1-3,5H3,(H,28,30,36)(H,29,31,32,33);2*4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t18-;2*16-;;;15-;;15-;;/m110..0.0../s1.
What are the key properties of N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide has a molecular weight of 5520.06 g/mol, XLogP of 50.94, 73 rotatable bonds, 20 hydrogen bond donors, and 100 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-[[5-tert-butyl-1-[[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]methyl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-4-fluoro-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]cyclopropanecarboxamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-(difluoromethyl)-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;bis(N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide);N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is sourced from PubChem (CID 167699175), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).