3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine

C10H6ClF3N4 — CID 169204837

IUPAC3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine
SMILESFC(F)(F)c1ccc(Nc2nccnc2Cl)nc1
InChIInChI=1S/C10H6ClF3N4/c11-8-9(16-4-3-15-8)18-7-2-1-6(5-17-7)10(12,13)14/h1-5H,(H,16,17,18)
InChIKeyRNEJWVLVOKFMGN-UHFFFAOYSA-N
MW274.63 g/mol
LogP3.29
Rot. Bonds2

About 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine

3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine (PubChem CID 169204837) has the molecular formula C10H6ClF3N4 and a molecular weight of 274.63 g/mol. Its IUPAC name is 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine.

Molecular Properties

Compound Name3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine
PubChem CID169204837
Molecular FormulaC10H6ClF3N4
Molecular Weight274.63 g/mol
Exact Mass274.02
IUPAC Name3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine
SMILESFC(F)(F)c1ccc(Nc2nccnc2Cl)nc1
InChIInChI=1S/C10H6ClF3N4/c11-8-9(16-4-3-15-8)18-7-2-1-6(5-17-7)10(12,13)14/h1-5H,(H,16,17,18)
InChIKeyRNEJWVLVOKFMGN-UHFFFAOYSA-N
XLogP3.29
TPSA50.70 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500274.63
LogP ≤ 53.29
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

3-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]pyrazin-2-amine
CID 62881850
[5-(trifluoromethyl)-2-pyridinyl]hydrazine
CID 1477642
2-chloro-5-[[5-(trifluoromethyl)-2-pyridinyl]amino]benzoic acid
CID 60862551
2-chloro-3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]pyrazine
CID 169204884
3-[4-[3-[[5-(trifluoromethyl)-2-pyridinyl]amino]pyrazin-2-yl]piperidin-1-yl]prop-2-enal
CID 174106919
N-(4-chlorobutyl)-5-(trifluoromethyl)pyridin-2-amine
CID 106845031
2-N-(2,6-dichlorophenyl)-5-methyl-7-N-[5-(trifluoromethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
CID 24883398
N-[(E)-3-methoxyprop-1-enyl]-5-(trifluoromethyl)pyridin-2-amine
CID 142991459
N-[2-(aminomethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine
CID 63765889
N-(5-chloropyrazin-2-yl)-5-(trifluoromethyl)pyridine-2-carboxamide
CID 107595663
7-(4-chloro-1,2,5-thiadiazol-3-yl)-N-[5-(trifluoromethyl)-2-pyridinyl]-1,8-naphthyridin-4-amine
CID 59705056
N-(3-methylbutan-2-yl)-5-(trifluoromethyl)pyridin-2-amine
CID 43084333

Frequently Asked Questions

What is the IUPAC name of 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine?
The IUPAC name of 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine (CID 169204837) is 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine.
What is the SMILES notation for 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine?
The canonical SMILES for 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine is FC(F)(F)c1ccc(Nc2nccnc2Cl)nc1.
What is the InChIKey of 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine?
The InChIKey is RNEJWVLVOKFMGN-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H6ClF3N4/c11-8-9(16-4-3-15-8)18-7-2-1-6(5-17-7)10(12,13)14/h1-5H,(H,16,17,18).
What are the key properties of 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine?
3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine has a molecular weight of 274.63 g/mol, XLogP of 3.29, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 3-chloro-N-[5-(trifluoromethyl)-2-pyridinyl]pyrazin-2-amine is sourced from PubChem (CID 169204837), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).