7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide

C20H21ClFN3O2 — CID 169241274

IUPAC7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide
SMILESCNCC(c1cc2c(c(-c3ccc(F)c(Cl)c3)n1)OCC2C(N)=O)C1CC1
InChIInChI=1S/C20H21ClFN3O2/c1-24-8-13(10-2-3-10)17-7-12-14(20(23)26)9-27-19(12)18(25-17)11-4-5-16(22)15(21)6-11/h4-7,10,13-14,24H,2-3,8-9H2,1H3,(H2,23,26)
InChIKeyVVGXDAYGJNWOIW-UHFFFAOYSA-N
MW389.86 g/mol
LogP3.22
Rot. Bonds6

About 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide

7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide (PubChem CID 169241274) has the molecular formula C20H21ClFN3O2 and a molecular weight of 389.86 g/mol. Its IUPAC name is 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide.

Molecular Properties

Compound Name7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide
PubChem CID169241274
Molecular FormulaC20H21ClFN3O2
Molecular Weight389.86 g/mol
Exact Mass389.13
IUPAC Name7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide
SMILESCNCC(c1cc2c(c(-c3ccc(F)c(Cl)c3)n1)OCC2C(N)=O)C1CC1
InChIInChI=1S/C20H21ClFN3O2/c1-24-8-13(10-2-3-10)17-7-12-14(20(23)26)9-27-19(12)18(25-17)11-4-5-16(22)15(21)6-11/h4-7,10,13-14,24H,2-3,8-9H2,1H3,(H2,23,26)
InChIKeyVVGXDAYGJNWOIW-UHFFFAOYSA-N
XLogP3.22
TPSA77.24 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds6
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500389.86
LogP ≤ 53.22
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide with MolForge

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Related Compounds

N-[2-[7-(3-chloro-4,5-difluorophenyl)-3-methyl-2,3-dihydrofuro[2,3-c]pyridin-5-yl]-2-cyclopropylethyl]formamide
CID 169240887
3-chloro-N-[2-[7-(4-chloro-3-fluorophenyl)-3-methyl-2,3-dihydrofuro[2,3-c]pyridin-5-yl]-2-cyclopropylethyl]-8-methoxy-2-methylquinoline-6-carboxamide;formaldehyde;methanamine
CID 164910750
8-chloro-3-methylquinoline-6-carbaldehyde;2-cyclopropyl-N-methyl-2-[3-methyl-7-(2,4,5-trifluorophenyl)-2,3-dihydrofuro[2,3-c]pyridin-5-yl]ethanamine;hydroxylamine
CID 164911339
4-(aziridin-2-yl)-2-(4-chloro-2,5-difluorophenyl)-6-[1-cyclopropyl-2-(methylamino)ethyl]pyridin-3-ol
CID 169241006
4-amino-N-[2-[7-(4-chloro-3-fluorophenyl)-3-methyl-2,3-dihydrofuro[2,3-c]pyridin-5-yl]-2-cyclopropylethyl]-3-[(E)-difluoromethyliminomethyl]-5-methoxybenzamide;formaldehyde;methanamine
CID 169241223
(3R)-7-(4-chloro-3-fluorophenyl)-5-[(1R)-2-[(3-chloro-8-methoxy-2-methylquinoline-6-carbonyl)amino]-1-cyclopropylethyl]-3-methyl-2H-furo[2,3-c]pyridine-3-carboxamide
CID 164910717
5-(2-amino-1-hydroxyethyl)-7-(3-chloro-4-fluorophenyl)-3-methyl-2H-furo[2,3-c]pyridin-3-ol
CID 134318749
2-cyclopropyl-N-[1-[2-(difluoromethyl)-7-methoxyindazol-5-yl]ethenyl]-2-[7-(4-fluorophenyl)-3-methyl-2,3-dihydrofuro[2,3-c]pyridin-5-yl]ethanamine
CID 169240906
2-amino-N-[(2R)-2-cyclopropyl-2-[7-(4-fluorophenyl)-3-(trifluoromethyl)-2,3-dihydrofuro[2,3-c]pyridin-5-yl]ethyl]-4-(trifluoromethoxy)-1,3-benzoxazole-6-carboxamide
CID 166672038
(3R)-5-[(1R)-1-cyclopropyl-2-[(2-cyclopropyl-8-methoxyimidazo[1,2-a]pyridine-6-carbonyl)amino]ethyl]-7-(3-fluoro-4-methylphenyl)-3-methyl-2H-furo[2,3-c]pyridine-3-carboxamide
CID 169241039
2-[6-(1-cyclopropyl-2-hydroxyethyl)-3-fluoro-2-(4-fluorophenyl)-4-pyridinyl]-2-methylpropanamide
CID 169264915
1-(3-chloro-4-fluorophenyl)-2-hydroxy-3-(methylamino)propan-1-one
CID 116826787

Frequently Asked Questions

What is the IUPAC name of 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide?
The IUPAC name of 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide (CID 169241274) is 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide.
What is the SMILES notation for 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide?
The canonical SMILES for 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide is CNCC(c1cc2c(c(-c3ccc(F)c(Cl)c3)n1)OCC2C(N)=O)C1CC1.
What is the InChIKey of 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide?
The InChIKey is VVGXDAYGJNWOIW-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H21ClFN3O2/c1-24-8-13(10-2-3-10)17-7-12-14(20(23)26)9-27-19(12)18(25-17)11-4-5-16(22)15(21)6-11/h4-7,10,13-14,24H,2-3,8-9H2,1H3,(H2,23,26).
What are the key properties of 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide?
7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide has a molecular weight of 389.86 g/mol, XLogP of 3.22, 6 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 7-(3-chloro-4-fluorophenyl)-5-[1-cyclopropyl-2-(methylamino)ethyl]-2,3-dihydrofuro[2,3-c]pyridine-3-carboxamide is sourced from PubChem (CID 169241274), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).