1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide

C8H8N4OS — CID 174854209

IUPAC1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide
SMILESNC(=O)C1=NC=CN(c2nccs2)C1
InChIInChI=1S/C8H8N4OS/c9-7(13)6-5-12(3-1-10-6)8-11-2-4-14-8/h1-4H,5H2,(H2,9,13)
InChIKeyZVCZTKFDYONHAM-UHFFFAOYSA-N
MW208.25 g/mol
LogP0.36
Rot. Bonds2

About 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide

1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide (PubChem CID 174854209) has the molecular formula C8H8N4OS and a molecular weight of 208.25 g/mol. Its IUPAC name is 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide.

Molecular Properties

Compound Name1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide
PubChem CID174854209
Molecular FormulaC8H8N4OS
Molecular Weight208.25 g/mol
Exact Mass208.04
IUPAC Name1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide
SMILESNC(=O)C1=NC=CN(c2nccs2)C1
InChIInChI=1S/C8H8N4OS/c9-7(13)6-5-12(3-1-10-6)8-11-2-4-14-8/h1-4H,5H2,(H2,9,13)
InChIKeyZVCZTKFDYONHAM-UHFFFAOYSA-N
XLogP0.36
TPSA71.58 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500208.25
LogP ≤ 50.36
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propanamide
CID 18136601
3-amino-1-(1,3-thiazol-2-yl)pyrazole-4-carboxamide
CID 82878352
N'-hydroxy-2,2-dimethyl-3-oxo-3-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propanimidamide
CID 76919935
3-(1,3-thiazol-2-yl)-7H-pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide
CID 67026510
4-amino-1-[4-(1,3-thiazol-2-yl)-1,4-diazepan-1-yl]butan-1-one;dihydrochloride
CID 119863990
1-[4-(1,3-thiazol-2-yl)piperazin-1-yl]butan-1-one
CID 158048076
cyclopropyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanone
CID 53498835
1,3-thiazol-2-amine;urea
CID 87216573
2-(4-methylidenepiperidin-1-yl)-1,3-thiazole
CID 55250932
5-[4-(1,3-thiazol-2-yl)piperazin-1-yl]pentanehydrazide
CID 63568871
N'-hydroxy-2-methyl-2-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propanimidamide
CID 77012304
2-amino-1-[4-(1,3-thiazol-2-yl)-1,4-diazepan-1-yl]ethanone
CID 83634826

Frequently Asked Questions

What is the IUPAC name of 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide?
The IUPAC name of 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide (CID 174854209) is 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide.
What is the SMILES notation for 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide?
The canonical SMILES for 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide is NC(=O)C1=NC=CN(c2nccs2)C1.
What is the InChIKey of 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide?
The InChIKey is ZVCZTKFDYONHAM-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H8N4OS/c9-7(13)6-5-12(3-1-10-6)8-11-2-4-14-8/h1-4H,5H2,(H2,9,13).
What are the key properties of 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide?
1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide has a molecular weight of 208.25 g/mol, XLogP of 0.36, 2 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(1,3-thiazol-2-yl)-2H-pyrazine-3-carboxamide is sourced from PubChem (CID 174854209), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).