N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide

C18H18F2N2O4S — CID 34431227

IUPACN-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide
SMILESO=C(Cc1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)NC2CC2)cc1
InChIInChI=1S/C18H18F2N2O4S/c19-18(20)26-15-7-1-12(2-8-15)11-17(23)21-13-5-9-16(10-6-13)27(24,25)22-14-3-4-14/h1-2,5-10,14,18,22H,3-4,11H2,(H,21,23)
InChIKeyJUBMDDQRYBXPED-UHFFFAOYSA-N
MW396.42 g/mol
LogP2.91
Rot. Bonds8

About N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide

N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide (PubChem CID 34431227) has the molecular formula C18H18F2N2O4S and a molecular weight of 396.42 g/mol. Its IUPAC name is N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide.

Molecular Properties

Compound NameN-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide
PubChem CID34431227
Molecular FormulaC18H18F2N2O4S
Molecular Weight396.42 g/mol
Exact Mass396.10
IUPAC NameN-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide
SMILESO=C(Cc1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)NC2CC2)cc1
InChIInChI=1S/C18H18F2N2O4S/c19-18(20)26-15-7-1-12(2-8-15)11-17(23)21-13-5-9-16(10-6-13)27(24,25)22-14-3-4-14/h1-2,5-10,14,18,22H,3-4,11H2,(H,21,23)
InChIKeyJUBMDDQRYBXPED-UHFFFAOYSA-N
XLogP2.91
TPSA84.50 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds8
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500396.42
LogP ≤ 52.91
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

2-[5-(cyclopropylsulfamoyl)-2-methoxyanilino]-N-[4-(difluoromethoxy)phenyl]acetamide
CID 37174879
N-(4-acetamidophenyl)-2-[4-(difluoromethoxy)phenyl]acetamide
CID 35049094
2-bromo-5-(cyclopropylsulfamoyl)-N-[4-(difluoromethoxy)phenyl]benzamide
CID 34274025
2-[4-(difluoromethoxy)phenyl]-N-(4-methylphenyl)acetamide
CID 33142215
N-[4-(cyclohexylsulfamoyl)phenyl]-2-phenylacetamide
CID 4627278
2-chloro-N-[4-(cyclopropylsulfamoyl)phenyl]acetamide
CID 43244647
N-[4-(difluoromethoxy)phenyl]-2-(4-nitrophenyl)acetamide
CID 9405238
N-[4-(difluoromethoxy)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamide
CID 27147330
3-(cyclopropylamino)-N-[4-(difluoromethoxy)phenyl]propanamide
CID 54924821
3-(benzenesulfonamido)-N-[4-(difluoromethoxy)phenyl]propanamide
CID 26800768
N-[4-(cyclopropylsulfamoyl)phenyl]-4-hydroxybutanamide
CID 79191548
2-[[4-(cyclopropylsulfamoyl)phenyl]methyl]-1-(4-propan-2-yloxyphenyl)guanidine;hydroiodide
CID 111072240

Frequently Asked Questions

What is the IUPAC name of N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide?
The IUPAC name of N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide (CID 34431227) is N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide.
What is the SMILES notation for N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide?
The canonical SMILES for N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide is O=C(Cc1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)NC2CC2)cc1.
What is the InChIKey of N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide?
The InChIKey is JUBMDDQRYBXPED-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18F2N2O4S/c19-18(20)26-15-7-1-12(2-8-15)11-17(23)21-13-5-9-16(10-6-13)27(24,25)22-14-3-4-14/h1-2,5-10,14,18,22H,3-4,11H2,(H,21,23).
What are the key properties of N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide?
N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide has a molecular weight of 396.42 g/mol, XLogP of 2.91, 8 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(cyclopropylsulfamoyl)phenyl]-2-[4-(difluoromethoxy)phenyl]acetamide is sourced from PubChem (CID 34431227), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).