3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide

C18H17ClF2N2O3 — CID 51195341

IUPAC3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide
SMILESCC(=O)NC(CC(=O)Nc1ccc(OC(F)F)cc1)c1ccc(Cl)cc1
InChIInChI=1S/C18H17ClF2N2O3/c1-11(24)22-16(12-2-4-13(19)5-3-12)10-17(25)23-14-6-8-15(9-7-14)26-18(20)21/h2-9,16,18H,10H2,1H3,(H,22,24)(H,23,25)
InChIKeyJPXZMPOBUQVRDH-UHFFFAOYSA-N
MW382.79 g/mol
LogP4.15
Rot. Bonds7

About 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide

3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide (PubChem CID 51195341) has the molecular formula C18H17ClF2N2O3 and a molecular weight of 382.79 g/mol. Its IUPAC name is 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide.

Molecular Properties

Compound Name3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide
PubChem CID51195341
Molecular FormulaC18H17ClF2N2O3
Molecular Weight382.79 g/mol
Exact Mass382.09
IUPAC Name3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide
SMILESCC(=O)NC(CC(=O)Nc1ccc(OC(F)F)cc1)c1ccc(Cl)cc1
InChIInChI=1S/C18H17ClF2N2O3/c1-11(24)22-16(12-2-4-13(19)5-3-12)10-17(25)23-14-6-8-15(9-7-14)26-18(20)21/h2-9,16,18H,10H2,1H3,(H,22,24)(H,23,25)
InChIKeyJPXZMPOBUQVRDH-UHFFFAOYSA-N
XLogP4.15
TPSA67.43 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds7
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500382.79
LogP ≤ 54.15
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

[2-[4-(difluoromethoxy)anilino]-2-oxoethyl] 3-acetamido-3-(4-chlorophenyl)propanoate
CID 46818457
(3S)-3-acetamido-N-[4-(difluoromethoxy)phenyl]-3-phenylpropanamide
CID 8502651
3-acetamido-3-(4-chlorophenyl)-N-(4-methoxyphenyl)propanamide
CID 46689011
3-acetamido-3-(4-chlorophenyl)-N-(4-methylphenyl)propanamide
CID 51194875
3-acetamido-3-(4-chlorophenyl)-N-(3,5-difluorophenyl)propanamide
CID 51271181
[2-(4-methoxyanilino)-2-oxoethyl] 3-acetamido-3-(4-chlorophenyl)propanoate
CID 55380350
methyl 3-(4-chlorophenyl)-3-[[2-[4-(difluoromethoxy)phenyl]acetyl]amino]propanoate
CID 55436102
3-acetamido-3-(4-methoxyphenyl)-N-[4-(trifluoromethyl)phenyl]propanamide
CID 46689046
3-acetamido-N-(3,5-dichlorophenyl)-3-(4-methylphenyl)propanamide
CID 55377328
3-acetamido-3-(4-chlorophenyl)-N-[2-(3,4-difluoroanilino)-2-oxoethyl]propanamide
CID 55379526
3-acetamido-3-(4-chlorophenyl)-N-[4-[(4-methylphenyl)sulfonylamino]phenyl]propanamide
CID 55377378
(3R)-3-acetamido-3-(4-methoxyphenyl)-N-(4-phenoxyphenyl)propanamide
CID 30685077

Frequently Asked Questions

What is the IUPAC name of 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide?
The IUPAC name of 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide (CID 51195341) is 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide.
What is the SMILES notation for 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide?
The canonical SMILES for 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide is CC(=O)NC(CC(=O)Nc1ccc(OC(F)F)cc1)c1ccc(Cl)cc1.
What is the InChIKey of 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide?
The InChIKey is JPXZMPOBUQVRDH-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H17ClF2N2O3/c1-11(24)22-16(12-2-4-13(19)5-3-12)10-17(25)23-14-6-8-15(9-7-14)26-18(20)21/h2-9,16,18H,10H2,1H3,(H,22,24)(H,23,25).
What are the key properties of 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide?
3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide has a molecular weight of 382.79 g/mol, XLogP of 4.15, 7 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 3-acetamido-3-(4-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]propanamide is sourced from PubChem (CID 51195341), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).