[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone

C14H16N4O2 — CID 60787653

IUPAC[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone
SMILESO=C(c1cn[nH]c1)N1CCN(c2ccc(O)cc2)CC1
InChIInChI=1S/C14H16N4O2/c19-13-3-1-12(2-4-13)17-5-7-18(8-6-17)14(20)11-9-15-16-10-11/h1-4,9-10,19H,5-8H2,(H,15,16)
InChIKeyGUVCJUNKRYUZJA-UHFFFAOYSA-N
MW272.31 g/mol
LogP1.08
Rot. Bonds2

About [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone

[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone (PubChem CID 60787653) has the molecular formula C14H16N4O2 and a molecular weight of 272.31 g/mol. Its IUPAC name is [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone.

Molecular Properties

Compound Name[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone
PubChem CID60787653
Molecular FormulaC14H16N4O2
Molecular Weight272.31 g/mol
Exact Mass272.13
IUPAC Name[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone
SMILESO=C(c1cn[nH]c1)N1CCN(c2ccc(O)cc2)CC1
InChIInChI=1S/C14H16N4O2/c19-13-3-1-12(2-4-13)17-5-7-18(8-6-17)14(20)11-9-15-16-10-11/h1-4,9-10,19H,5-8H2,(H,15,16)
InChIKeyGUVCJUNKRYUZJA-UHFFFAOYSA-N
XLogP1.08
TPSA72.46 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500272.31
LogP ≤ 51.08
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1H-pyrazol-4-yl-(4-pyridin-3-ylpiperazin-1-yl)methanone
CID 77082727
azetidin-1-yl(1H-pyrazol-4-yl)methanone
CID 130157927
[4-(4-hydroxyphenyl)piperazin-1-yl]-(4-iodophenyl)methanone
CID 2451417
[4-(4-hydroxyphenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CID 8779428
[4-(1H-pyrazole-4-carbonyl)piperazin-1-yl]-thiophen-2-ylmethanone
CID 60788153
3-propan-2-yl-7-[4-(1H-pyrazole-4-carbonyl)piperazin-1-yl]quinazolin-4-one
CID 126897276
(4-propylpiperazin-1-yl)-(1H-pyrazol-4-yl)methanone
CID 43582709
[4-(2-bromoethyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone
CID 80660526
[4-(4-hydroxyphenyl)piperazin-1-yl]-naphthalen-2-ylmethanone
CID 2120761
[4-(4-hydroxyphenyl)piperazin-1-yl]-[4-(trifluoromethyl)phenyl]methanone
CID 8779377
(3,5-dimethoxy-4-methylphenyl)-[4-(4-hydroxyphenyl)piperazin-1-yl]methanone
CID 78777604
2-[4-(1H-pyrazole-4-carbonyl)piperazin-1-yl]pyridine-4-carbonitrile
CID 167778065

Frequently Asked Questions

What is the IUPAC name of [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone?
The IUPAC name of [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone (CID 60787653) is [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone.
What is the SMILES notation for [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone?
The canonical SMILES for [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone is O=C(c1cn[nH]c1)N1CCN(c2ccc(O)cc2)CC1.
What is the InChIKey of [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone?
The InChIKey is GUVCJUNKRYUZJA-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H16N4O2/c19-13-3-1-12(2-4-13)17-5-7-18(8-6-17)14(20)11-9-15-16-10-11/h1-4,9-10,19H,5-8H2,(H,15,16).
What are the key properties of [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone?
[4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone has a molecular weight of 272.31 g/mol, XLogP of 1.08, 2 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for [4-(4-hydroxyphenyl)piperazin-1-yl]-(1H-pyrazol-4-yl)methanone is sourced from PubChem (CID 60787653), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).