4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide

C19H19F3N2O2 — CID 6459805

IUPAC4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
SMILESO=C(Nc1ccccc1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1
InChIInChI=1S/C19H19F3N2O2/c20-19(21,22)15-6-4-5-14(13-15)18(26)9-11-24(12-10-18)17(25)23-16-7-2-1-3-8-16/h1-8,13,26H,9-12H2,(H,23,25)
InChIKeyIDHRCLPDDUBYEW-UHFFFAOYSA-N
MW364.37 g/mol
LogP4.22
Rot. Bonds2

About 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide

4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide (PubChem CID 6459805) has the molecular formula C19H19F3N2O2 and a molecular weight of 364.37 g/mol. Its IUPAC name is 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide.

Molecular Properties

Compound Name4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
PubChem CID6459805
Molecular FormulaC19H19F3N2O2
Molecular Weight364.37 g/mol
Exact Mass364.14
IUPAC Name4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
SMILESO=C(Nc1ccccc1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1
InChIInChI=1S/C19H19F3N2O2/c20-19(21,22)15-6-4-5-14(13-15)18(26)9-11-24(12-10-18)17(25)23-16-7-2-1-3-8-16/h1-8,13,26H,9-12H2,(H,23,25)
InChIKeyIDHRCLPDDUBYEW-UHFFFAOYSA-N
XLogP4.22
TPSA52.57 Ų
H-Bond Donors2
H-Bond Acceptors2
Rotatable Bonds2
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500364.37
LogP ≤ 54.22
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 102

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Related Compounds

N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-phenethylmorpholine-4-carboxamide
CID 10277212
1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(2,5-difluoro-phenyl)-urea
CID 11134412
1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-phenyl-urea
CID 11732727
4-[hydroxy(diphenyl)methyl]-N-[4-(trifluoromethyl)phenyl]piperidine-1-carbothioamide
CID 17312686
4-(4-bromophenyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-hydroxypiperidine-1-carboxamide
CID 23071887
Propionanilide, N-(1-(4-hydroxy-4-(alpha,alpha,alpha-trifluoro-m-tolyl)piperidino)-2-propyl)-, hydrochloride
CID 380231
N-[4-(dimethylamino)phenyl]-2-(4-hydroxy-4-phenyl-piperidino)acetamide
CID 3228763
1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-3-phenyl-urea
CID 10863252
6-(3-Ethyl-4-methyl-phenylamino)-3-[4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butyl]-1H-pyrimidine-2,4-dione
CID 10928878
1-Ethyl-3,3-dimethyl-1-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]urea
CID 11646151
3-[(dimethylamino)methyl]-4-hydroxy-N,4-diphenylpiperidine-1-carboxamide;hydrochloride
CID 162655156
3-[(dimethylamino)methyl]-4-hydroxy-4-(3-hydroxyphenyl)-N-phenylpiperidine-1-carboxamide;hydrochloride
CID 162667204

Frequently Asked Questions

What is the IUPAC name of 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The IUPAC name of 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide (CID 6459805) is 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide.
What is the SMILES notation for 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The canonical SMILES for 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide is O=C(Nc1ccccc1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1.
What is the InChIKey of 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
The InChIKey is IDHRCLPDDUBYEW-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19F3N2O2/c20-19(21,22)15-6-4-5-14(13-15)18(26)9-11-24(12-10-18)17(25)23-16-7-2-1-3-8-16/h1-8,13,26H,9-12H2,(H,23,25).
What are the key properties of 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide?
4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide has a molecular weight of 364.37 g/mol, XLogP of 4.22, 2 rotatable bonds, 2 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 4-hydroxy-N-phenyl-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide is sourced from PubChem (CID 6459805), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).