N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine

C11H15F3N2S — CID 66352549

IUPACN-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine
SMILESFC(F)(F)CN1CCC(Nc2ccsc2)CC1
InChIInChI=1S/C11H15F3N2S/c12-11(13,14)8-16-4-1-9(2-5-16)15-10-3-6-17-7-10/h3,6-7,9,15H,1-2,4-5,8H2
InChIKeyRWTFMJLJEZAMCD-UHFFFAOYSA-N
MW264.32 g/mol
LogP3.19
Rot. Bonds3

About N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine

N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine (PubChem CID 66352549) has the molecular formula C11H15F3N2S and a molecular weight of 264.32 g/mol. Its IUPAC name is N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine.

Molecular Properties

Compound NameN-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine
PubChem CID66352549
Molecular FormulaC11H15F3N2S
Molecular Weight264.32 g/mol
Exact Mass264.09
IUPAC NameN-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine
SMILESFC(F)(F)CN1CCC(Nc2ccsc2)CC1
InChIInChI=1S/C11H15F3N2S/c12-11(13,14)8-16-4-1-9(2-5-16)15-10-3-6-17-7-10/h3,6-7,9,15H,1-2,4-5,8H2
InChIKeyRWTFMJLJEZAMCD-UHFFFAOYSA-N
XLogP3.19
TPSA15.27 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds3
Heavy Atoms17
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500264.32
LogP ≤ 53.19
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

1-propyl-N-thiophen-3-ylpiperidin-4-amine
CID 66352075
4-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]benzene-1,4-diamine
CID 144655800
1-(3-methylbut-2-enyl)-N-thiophen-3-ylpiperidin-4-amine
CID 66350332
1-propyl-N-thiophen-3-ylazepan-4-amine
CID 66351874
N-(4-propan-2-ylphenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 43760602
1-methyl-5-[[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]pyridin-2-one
CID 60932164
N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]-1,3,4-thiadiazol-2-amine
CID 107648861
N-(3-bromo-5-methylphenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 104938423
N-(4-chloro-2-fluorophenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 43785130
N-(3-chloro-2-fluorophenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 43772940
N-(4-iodo-2-methylphenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 43785266
N-(2-bromo-5-chlorophenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine
CID 81270640

Frequently Asked Questions

What is the IUPAC name of N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine?
The IUPAC name of N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine (CID 66352549) is N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine.
What is the SMILES notation for N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine?
The canonical SMILES for N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine is FC(F)(F)CN1CCC(Nc2ccsc2)CC1.
What is the InChIKey of N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine?
The InChIKey is RWTFMJLJEZAMCD-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H15F3N2S/c12-11(13,14)8-16-4-1-9(2-5-16)15-10-3-6-17-7-10/h3,6-7,9,15H,1-2,4-5,8H2.
What are the key properties of N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine?
N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine has a molecular weight of 264.32 g/mol, XLogP of 3.19, 3 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for N-thiophen-3-yl-1-(2,2,2-trifluoroethyl)piperidin-4-amine is sourced from PubChem (CID 66352549), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).