4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide

C18H12ClFN2O2 — CID 66806391

IUPAC4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
SMILESNC(=O)c1cc(Cl)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1
InChIInChI=1S/C18H12ClFN2O2/c19-12-9-16(22-17(10-12)18(21)23)11-1-5-14(6-2-11)24-15-7-3-13(20)4-8-15/h1-10H,(H2,21,23)
InChIKeyRTEVQCDDTKYWET-UHFFFAOYSA-N
MW342.76 g/mol
LogP4.43
Rot. Bonds4

About 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide

4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide (PubChem CID 66806391) has the molecular formula C18H12ClFN2O2 and a molecular weight of 342.76 g/mol. Its IUPAC name is 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide.

Molecular Properties

Compound Name4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
PubChem CID66806391
Molecular FormulaC18H12ClFN2O2
Molecular Weight342.76 g/mol
Exact Mass342.06
IUPAC Name4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
SMILESNC(=O)c1cc(Cl)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1
InChIInChI=1S/C18H12ClFN2O2/c19-12-9-16(22-17(10-12)18(21)23)11-1-5-14(6-2-11)24-15-7-3-13(20)4-8-15/h1-10H,(H2,21,23)
InChIKeyRTEVQCDDTKYWET-UHFFFAOYSA-N
XLogP4.43
TPSA65.21 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds4
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500342.76
LogP ≤ 54.43
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

4-[(2R)-2,3-dihydroxypropyl]-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
CID 66799547
4-(N-(2-amino-2-oxoethyl)anilino)-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
CID 66799553
6-[4-(4-fluorophenoxy)phenyl]-4-(pyrimidin-2-ylmethylamino)pyridine-2-carboxamide
CID 56943461
6-[4-(4-fluorophenoxy)phenyl]-2-[[(2S)-3-oxobutan-2-yl]amino]pyrimidine-4-carboxamide
CID 118653205
1-[4-chloro-6-[4-(4-fluorophenoxy)phenyl]-2-pyridinyl]piperidine-4-carboxylic acid
CID 57405385
6-[(1S)-1,2-dihydroxyethyl]-4-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
CID 56943193
6-[(1R)-1,2-dihydroxyethyl]-2-[4-(4-fluorophenoxy)phenyl]pyrimidine-4-carboxamide
CID 71571985
4-[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethylamino]-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide
CID 66799580
6-[4-(4-fluorophenoxy)phenyl]-4-[[2-(2-oxoimidazolidin-1-yl)ethylamino]methyl]pyridine-2-carboxamide
CID 56943523
4-[(1R)-1,2-dihydroxyethyl]-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxylic acid
CID 66668235
4-(1,2-dihydroxyethyl)-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxylic acid
CID 66668236
6-[(2-amino-2-oxoethyl)amino]-2-[4-(4-fluorophenoxy)phenyl]pyrimidine-4-carboxamide
CID 71283530

Frequently Asked Questions

What is the IUPAC name of 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide?
The IUPAC name of 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide (CID 66806391) is 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide.
What is the SMILES notation for 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide?
The canonical SMILES for 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide is NC(=O)c1cc(Cl)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1.
What is the InChIKey of 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide?
The InChIKey is RTEVQCDDTKYWET-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H12ClFN2O2/c19-12-9-16(22-17(10-12)18(21)23)11-1-5-14(6-2-11)24-15-7-3-13(20)4-8-15/h1-10H,(H2,21,23).
What are the key properties of 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide?
4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide has a molecular weight of 342.76 g/mol, XLogP of 4.43, 4 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 4-chloro-6-[4-(4-fluorophenoxy)phenyl]pyridine-2-carboxamide is sourced from PubChem (CID 66806391), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).