5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one

C23H26N2O3 — CID 70630676

IUPAC5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one
SMILESCOc1ccc(C(O)CN2CCC(c3ccccc3)CC2)c2ccc(=O)[nH]c12
InChIInChI=1S/C23H26N2O3/c1-28-21-9-7-18(19-8-10-22(27)24-23(19)21)20(26)15-25-13-11-17(12-14-25)16-5-3-2-4-6-16/h2-10,17,20,26H,11-15H2,1H3,(H,24,27)
InChIKeyGNJQTDLQMCHNSP-UHFFFAOYSA-N
MW378.47 g/mol
LogP3.45
Rot. Bonds5

About 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one

5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one (PubChem CID 70630676) has the molecular formula C23H26N2O3 and a molecular weight of 378.47 g/mol. Its IUPAC name is 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one.

Molecular Properties

Compound Name5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one
PubChem CID70630676
Molecular FormulaC23H26N2O3
Molecular Weight378.47 g/mol
Exact Mass378.19
IUPAC Name5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one
SMILESCOc1ccc(C(O)CN2CCC(c3ccccc3)CC2)c2ccc(=O)[nH]c12
InChIInChI=1S/C23H26N2O3/c1-28-21-9-7-18(19-8-10-22(27)24-23(19)21)20(26)15-25-13-11-17(12-14-25)16-5-3-2-4-6-16/h2-10,17,20,26H,11-15H2,1H3,(H,24,27)
InChIKeyGNJQTDLQMCHNSP-UHFFFAOYSA-N
XLogP3.45
TPSA65.56 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500378.47
LogP ≤ 53.45
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[3-[1-[4-[[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-2-methoxybenzoyl]piperidin-4-yl]phenyl]-2-phenylacetaldehyde
CID 155441106
5-[(1R)-2-[(4,7-dimethoxy-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
CID 11386205
5-[1-hydroxy-2-[(1-methylsulfonylpiperidin-4-yl)amino]ethyl]-8-phenylmethoxy-1H-quinolin-2-one
CID 175378779
(1R)-1-(4-bromophenyl)-2-(4-phenylpiperidin-1-yl)ethanol
CID 15048614
5-[1-(8-methoxy-2-oxo-1H-quinolin-5-yl)ethyl]-1,3-thiazolidine-2,4-dione
CID 87066059
2-(4-phenylpiperidin-1-yl)-1-(4-tributylstannylphenyl)ethanol
CID 19696304
1-(4-phenylpiperidin-1-yl)-3-piperidin-1-ylpropan-2-ol
CID 3030548
5-[(1R)-1-hydroxy-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-8-phenylmethoxy-1H-quinolin-2-one
CID 91493260
1-(2-methoxyphenyl)-2-(4-propylpiperidin-1-yl)ethanol
CID 62205945
N-benzyl-3-[4-[[[(2S)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]piperidin-1-yl]propanamide
CID 68927952
N-benzyl-3-[4-[[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]piperidin-1-yl]propanamide
CID 143535728
5-[(1R)-2-[(2-benzylcyclopentyl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
CID 69039761

Frequently Asked Questions

What is the IUPAC name of 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one?
The IUPAC name of 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one (CID 70630676) is 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one.
What is the SMILES notation for 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one?
The canonical SMILES for 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one is COc1ccc(C(O)CN2CCC(c3ccccc3)CC2)c2ccc(=O)[nH]c12.
What is the InChIKey of 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one?
The InChIKey is GNJQTDLQMCHNSP-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26N2O3/c1-28-21-9-7-18(19-8-10-22(27)24-23(19)21)20(26)15-25-13-11-17(12-14-25)16-5-3-2-4-6-16/h2-10,17,20,26H,11-15H2,1H3,(H,24,27).
What are the key properties of 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one?
5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one has a molecular weight of 378.47 g/mol, XLogP of 3.45, 5 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[1-hydroxy-2-(4-phenylpiperidin-1-yl)ethyl]-8-methoxy-1H-quinolin-2-one is sourced from PubChem (CID 70630676), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).