8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

C25H21F2N3O4 — CID 71479016

IUPAC8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
SMILESCc1nc2c(OCc3cccc(F)c3F)cccn2c1C(=O)NC1c2ccccc2[C@H](O)[C@H]1O
InChIInChI=1S/C25H21F2N3O4/c1-13-21(25(33)29-20-15-7-2-3-8-16(15)22(31)23(20)32)30-11-5-10-18(24(30)28-13)34-12-14-6-4-9-17(26)19(14)27/h2-11,20,22-23,31-32H,12H2,1H3,(H,29,33)/t20?,22-,23-/m0/s1
InChIKeyZUXQRVNFXHXKDV-FALYVICWSA-N
MW465.46 g/mol
LogP3.38
Rot. Bonds5

About 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 71479016) has the molecular formula C25H21F2N3O4 and a molecular weight of 465.46 g/mol. Its IUPAC name is 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

Compound Name8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
PubChem CID71479016
Molecular FormulaC25H21F2N3O4
Molecular Weight465.46 g/mol
Exact Mass465.15
IUPAC Name8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
SMILESCc1nc2c(OCc3cccc(F)c3F)cccn2c1C(=O)NC1c2ccccc2[C@H](O)[C@H]1O
InChIInChI=1S/C25H21F2N3O4/c1-13-21(25(33)29-20-15-7-2-3-8-16(15)22(31)23(20)32)30-11-5-10-18(24(30)28-13)34-12-14-6-4-9-17(26)19(14)27/h2-11,20,22-23,31-32H,12H2,1H3,(H,29,33)/t20?,22-,23-/m0/s1
InChIKeyZUXQRVNFXHXKDV-FALYVICWSA-N
XLogP3.38
TPSA96.09 Ų
H-Bond Donors3
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500465.46
LogP ≤ 53.38
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 106

Analyze 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(1R,2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-8-[(2-fluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 71478863
(1S,2R)-1-[[8-[(2,6-difluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine-3-carbonyl]amino]-4-methyl-2,3-dihydro-1H-indene-2-carboxylic acid
CID 71478606
(4S,5R)-4-[[8-[(2,6-difluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine-3-carbonyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-5-carboxylic acid
CID 90090958
8-[(2,6-difluorophenyl)methoxy]-2-methyl-N-[(3S)-1-methylpiperidin-3-yl]imidazo[1,2-a]pyridine-3-carboxamide;methane
CID 157110920
8-[(2-fluorophenyl)methoxy]-N-[2-[4-(hydroxymethyl)phenyl]propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 144635819
8-[(2,6-difluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine-3-carbonyl chloride
CID 86717886
8-[(2,6-difluorophenyl)methoxy]-N-(3-hydroxybutyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90135188
8-[(2,6-difluorophenyl)methoxy]-2-methyl-N-(6-methyl-2-pyridinyl)imidazo[1,2-a]pyridine-3-carboxamide
CID 118144957
1-[8-[(2,6-difluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl]-2-[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]ethanone
CID 159220216
1-[8-[(2,6-difluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl]-2-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]ethanone
CID 159220214
8-ethoxy-N-[(3R,4R)-4-hydroxypyrrolidin-3-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90090266
8-[(2,6-difluorophenyl)methoxy]-N-(4,5-dimethyl-1,3-oxazol-2-yl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 118144801

Frequently Asked Questions

What is the IUPAC name of 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The IUPAC name of 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CID 71479016) is 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.
What is the SMILES notation for 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The canonical SMILES for 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is Cc1nc2c(OCc3cccc(F)c3F)cccn2c1C(=O)NC1c2ccccc2[C@H](O)[C@H]1O.
What is the InChIKey of 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The InChIKey is ZUXQRVNFXHXKDV-FALYVICWSA-N. The full InChI is InChI=1S/C25H21F2N3O4/c1-13-21(25(33)29-20-15-7-2-3-8-16(15)22(31)23(20)32)30-11-5-10-18(24(30)28-13)34-12-14-6-4-9-17(26)19(14)27/h2-11,20,22-23,31-32H,12H2,1H3,(H,29,33)/t20?,22-,23-/m0/s1.
What are the key properties of 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 465.46 g/mol, XLogP of 3.38, 5 rotatable bonds, 3 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 8-[(2,3-difluorophenyl)methoxy]-N-[(2S,3S)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 71479016), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).