6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine

C14H16N6S — CID 75075517

IUPAC6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine
SMILESc1cn2c(-c3cncc(NC4CCCNC4)n3)cnc2s1
InChIInChI=1S/C14H16N6S/c1-2-10(6-15-3-1)18-13-9-16-7-11(19-13)12-8-17-14-20(12)4-5-21-14/h4-5,7-10,15H,1-3,6H2,(H,18,19)
InChIKeyOFRJRNZWYUNFLJ-UHFFFAOYSA-N
MW300.39 g/mol
LogP2.02
Rot. Bonds3

About 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine

6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine (PubChem CID 75075517) has the molecular formula C14H16N6S and a molecular weight of 300.39 g/mol. Its IUPAC name is 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine.

Molecular Properties

Compound Name6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine
PubChem CID75075517
Molecular FormulaC14H16N6S
Molecular Weight300.39 g/mol
Exact Mass300.12
IUPAC Name6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine
SMILESc1cn2c(-c3cncc(NC4CCCNC4)n3)cnc2s1
InChIInChI=1S/C14H16N6S/c1-2-10(6-15-3-1)18-13-9-16-7-11(19-13)12-8-17-14-20(12)4-5-21-14/h4-5,7-10,15H,1-3,6H2,(H,18,19)
InChIKeyOFRJRNZWYUNFLJ-UHFFFAOYSA-N
XLogP2.02
TPSA67.14 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds3
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500300.39
LogP ≤ 52.02
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(3R,4R)-4-(fluoromethyl)pyrrolidin-3-yl]-6-(2-propan-2-ylimidazo[2,1-b][1,3]thiazol-5-yl)pyrazin-2-amine
CID 58303384
N-[(3R,4R)-4-(fluoromethyl)pyrrolidin-3-yl]-6-imidazo[2,1-b][1,3]thiazol-5-ylpyrazin-2-amine
CID 58303462
N-[(3R,4R)-4-(fluoromethyl)pyrrolidin-3-yl]-6-(2-methylimidazo[2,1-b][1,3]thiazol-5-yl)pyrazin-2-amine
CID 58303502
6-(2-ethylimidazo[2,1-b][1,3]thiazol-5-yl)-N-[(3R,4R)-4-(fluoromethyl)pyrrolidin-3-yl]pyrazin-2-amine
CID 58303564
N-[(3R,4S)-4-(fluoromethyl)pyrrolidin-3-yl]-6-(2-propan-2-ylimidazo[2,1-b][1,3]thiazol-5-yl)pyrazin-2-amine
CID 66670575
N-[4-(fluoromethyl)pyrrolidin-3-yl]-6-(2-propan-2-ylimidazo[2,1-b][1,3]thiazol-5-yl)pyrazin-2-amine
CID 76753468
N-[4-(fluoromethyl)pyrrolidin-3-yl]-6-imidazo[2,1-b][1,3]thiazol-5-ylpyrazin-2-amine
CID 76753513
N-[4-(fluoromethyl)pyrrolidin-3-yl]-6-(2-methylimidazo[2,1-b][1,3]thiazol-5-yl)pyrazin-2-amine
CID 76753533
6-(2-ethylimidazo[2,1-b][1,3]thiazol-5-yl)-N-[4-(fluoromethyl)pyrrolidin-3-yl]pyrazin-2-amine
CID 76753571
Methylsulfanylmethane;1-[2-[2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazol-5-yl]pyrimidin-4-yl]piperidin-3-amine
CID 153330896
N-[1-({imidazo[2,1-b][1,3]thiazol-6-yl}methyl)piperidin-4-yl]-6-(trifluoromethyl)pyrimidin-4-amine
CID 126889714
5-fluoro-N-(2-imidazo[2,1-b][1,3]thiazol-6-ylethyl)-4-pyrrolidin-1-ylpyrimidin-2-amine
CID 134707806

Frequently Asked Questions

What is the IUPAC name of 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine?
The IUPAC name of 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine (CID 75075517) is 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine.
What is the SMILES notation for 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine?
The canonical SMILES for 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine is c1cn2c(-c3cncc(NC4CCCNC4)n3)cnc2s1.
What is the InChIKey of 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine?
The InChIKey is OFRJRNZWYUNFLJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H16N6S/c1-2-10(6-15-3-1)18-13-9-16-7-11(19-13)12-8-17-14-20(12)4-5-21-14/h4-5,7-10,15H,1-3,6H2,(H,18,19).
What are the key properties of 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine?
6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine has a molecular weight of 300.39 g/mol, XLogP of 2.02, 3 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 6-imidazo[2,1-b][1,3]thiazol-5-yl-N-piperidin-3-ylpyrazin-2-amine is sourced from PubChem (CID 75075517), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).