4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol

C14H19F2NO — CID 80604289

IUPAC4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol
SMILESOC1(C(F)F)CCN(CCc2ccccc2)CC1
InChIInChI=1S/C14H19F2NO/c15-13(16)14(18)7-10-17(11-8-14)9-6-12-4-2-1-3-5-12/h1-5,13,18H,6-11H2
InChIKeySMQZIEXIVBUUAI-UHFFFAOYSA-N
MW255.31 g/mol
LogP2.32
Rot. Bonds4

About 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol

4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol (PubChem CID 80604289) has the molecular formula C14H19F2NO and a molecular weight of 255.31 g/mol. Its IUPAC name is 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol.

Molecular Properties

Compound Name4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol
PubChem CID80604289
Molecular FormulaC14H19F2NO
Molecular Weight255.31 g/mol
Exact Mass255.14
IUPAC Name4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol
SMILESOC1(C(F)F)CCN(CCc2ccccc2)CC1
InChIInChI=1S/C14H19F2NO/c15-13(16)14(18)7-10-17(11-8-14)9-6-12-4-2-1-3-5-12/h1-5,13,18H,6-11H2
InChIKeySMQZIEXIVBUUAI-UHFFFAOYSA-N
XLogP2.32
TPSA23.47 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds4
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500255.31
LogP ≤ 52.32
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

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Related Compounds

1-benzyl-3-(difluoromethyl)pyrrolidin-3-ol
CID 80605715
4-methyl-1-(2-phenylethyl)azepan-4-ol
CID 107408153
1-[4-hydroxy-1-(2-phenylethyl)piperidin-4-yl]propyl propanoate
CID 174713677
4-(difluoromethyl)-1-(2-phenylethyl)-N-propylpiperidin-4-amine
CID 80610896
4-benzyl-1-(2-phenylethyl)piperidine-4-carboxylic acid
CID 122657647
(1S,3R)-7-(2-phenylethyl)-7-azaspiro[3.5]nonane-1,3-diol
CID 72916080
4-(nitromethyl)-1-(2-phenylethyl)piperidin-4-ol
CID 73332914
5-(2-phenylethyl)-5-azaspiro[2.4]heptane
CID 142337171
4-(4-bromoisoquinolin-1-yl)-1-(2-phenylethyl)piperidin-4-ol
CID 13466237
N-[[4-hydroxy-1-(2-phenylethyl)piperidin-4-yl]methyl]acetamide
CID 165352141
1-(2-chloroethyl)-4-(2-phenylethyl)piperazine
CID 10264250
[4-(2-phenoxyethyl)-1-(2-phenylethyl)piperidin-4-yl]methanol
CID 126461306

Frequently Asked Questions

What is the IUPAC name of 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol?
The IUPAC name of 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol (CID 80604289) is 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol.
What is the SMILES notation for 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol?
The canonical SMILES for 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol is OC1(C(F)F)CCN(CCc2ccccc2)CC1.
What is the InChIKey of 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol?
The InChIKey is SMQZIEXIVBUUAI-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H19F2NO/c15-13(16)14(18)7-10-17(11-8-14)9-6-12-4-2-1-3-5-12/h1-5,13,18H,6-11H2.
What are the key properties of 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol?
4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol has a molecular weight of 255.31 g/mol, XLogP of 2.32, 4 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(difluoromethyl)-1-(2-phenylethyl)piperidin-4-ol is sourced from PubChem (CID 80604289), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).