1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine

C14H20F2N2S — CID 83993153

IUPAC1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine
SMILESFC(F)CNC1CC(c2cccs2)CN(C2CC2)C1
InChIInChI=1S/C14H20F2N2S/c15-14(16)7-17-11-6-10(13-2-1-5-19-13)8-18(9-11)12-3-4-12/h1-2,5,10-12,14,17H,3-4,6-9H2
InChIKeyGHIFDZFMARXLOL-UHFFFAOYSA-N
MW286.39 g/mol
LogP2.92
Rot. Bonds5

About 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine

1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine (PubChem CID 83993153) has the molecular formula C14H20F2N2S and a molecular weight of 286.39 g/mol. Its IUPAC name is 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine.

Molecular Properties

Compound Name1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine
PubChem CID83993153
Molecular FormulaC14H20F2N2S
Molecular Weight286.39 g/mol
Exact Mass286.13
IUPAC Name1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine
SMILESFC(F)CNC1CC(c2cccs2)CN(C2CC2)C1
InChIInChI=1S/C14H20F2N2S/c15-14(16)7-17-11-6-10(13-2-1-5-19-13)8-18(9-11)12-3-4-12/h1-2,5,10-12,14,17H,3-4,6-9H2
InChIKeyGHIFDZFMARXLOL-UHFFFAOYSA-N
XLogP2.92
TPSA15.27 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds5
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500286.39
LogP ≤ 52.92
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

N-(2,2-difluoroethyl)-1-ethyl-5-thiophen-2-ylpiperidin-3-amine
CID 83992794
N-(cyclohexylmethyl)-1-cyclopropyl-5-thiophen-2-ylpiperidin-3-amine
CID 83998686
methyl N-(1-cyclopropyl-5-thiophen-2-ylpiperidin-3-yl)carbamate
CID 112543340
1-ethyl-N-methyl-5-thiophen-2-ylpiperidin-3-amine
CID 83989566
1-[1-cyclopropyl-5-(2,2-difluoroethylamino)piperidin-3-yl]ethanol
CID 83993163
1-methyl-5-thiophen-2-yl-N-(2,2,2-trifluoroethyl)piperidin-3-amine
CID 83992062
N-(cyclohexylmethyl)-1-methyl-5-thiophen-2-ylpiperidin-3-amine
CID 83998289
1-cyclohexyl-N-(2,2-difluoroethyl)-5-methylpiperidin-3-amine
CID 83993171
1-cyclopropyl-N-ethyl-5-phenylpiperidin-3-amine
CID 83990517
methyl 2-[1-cyclopropyl-5-(2,2-difluoroethylamino)piperidin-3-yl]acetate
CID 83993158
methyl 1-cyclopentyl-5-(2,2-difluoroethylamino)piperidine-3-carboxylate
CID 83993140
N-(1-propan-2-yl-5-thiophen-2-ylpiperidin-3-yl)acetamide
CID 112541749

Frequently Asked Questions

What is the IUPAC name of 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine?
The IUPAC name of 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine (CID 83993153) is 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine.
What is the SMILES notation for 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine?
The canonical SMILES for 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine is FC(F)CNC1CC(c2cccs2)CN(C2CC2)C1.
What is the InChIKey of 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine?
The InChIKey is GHIFDZFMARXLOL-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H20F2N2S/c15-14(16)7-17-11-6-10(13-2-1-5-19-13)8-18(9-11)12-3-4-12/h1-2,5,10-12,14,17H,3-4,6-9H2.
What are the key properties of 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine?
1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine has a molecular weight of 286.39 g/mol, XLogP of 2.92, 5 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 1-cyclopropyl-N-(2,2-difluoroethyl)-5-thiophen-2-ylpiperidin-3-amine is sourced from PubChem (CID 83993153), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).