(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide

C21H22N2O2S — CID 8512914

IUPAC(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide
SMILESCOc1ccc(C)cc1NC(=O)[C@H](NCc1cccs1)c1ccccc1
InChIInChI=1S/C21H22N2O2S/c1-15-10-11-19(25-2)18(13-15)23-21(24)20(16-7-4-3-5-8-16)22-14-17-9-6-12-26-17/h3-13,20,22H,14H2,1-2H3,(H,23,24)/t20-/m1/s1
InChIKeyRFSZZHAMOCZYAR-HXUWFJFHSA-N
MW366.49 g/mol
LogP4.53
Rot. Bonds7

About (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide

(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide (PubChem CID 8512914) has the molecular formula C21H22N2O2S and a molecular weight of 366.49 g/mol. Its IUPAC name is (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide.

Molecular Properties

Compound Name(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide
PubChem CID8512914
Molecular FormulaC21H22N2O2S
Molecular Weight366.49 g/mol
Exact Mass366.14
IUPAC Name(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide
SMILESCOc1ccc(C)cc1NC(=O)[C@H](NCc1cccs1)c1ccccc1
InChIInChI=1S/C21H22N2O2S/c1-15-10-11-19(25-2)18(13-15)23-21(24)20(16-7-4-3-5-8-16)22-14-17-9-6-12-26-17/h3-13,20,22H,14H2,1-2H3,(H,23,24)/t20-/m1/s1
InChIKeyRFSZZHAMOCZYAR-HXUWFJFHSA-N
XLogP4.53
TPSA50.36 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds7
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500366.49
LogP ≤ 54.53
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

4-[[[(1S)-2-(2-methoxy-5-methylanilino)-2-oxo-1-phenylethyl]amino]methyl]benzoic acid
CID 40843286
(2R)-2-[[(2S)-2-hydroxy-2-phenylethyl]amino]-N-(2-methoxy-5-methylphenyl)-2-phenylacetamide
CID 2434114
ethyl-[(1R)-2-(2-methoxy-5-methylanilino)-2-oxo-1-phenylethyl]-(thiophen-2-ylmethyl)azanium
CID 8718246
(2R)-N-(2-methoxy-5-methylphenyl)-2-(2-methylbutan-2-ylamino)-2-phenylacetamide
CID 9267285
(2R)-2-methoxy-N-(2-methoxy-5-methylphenyl)-2-phenylacetamide
CID 883174
(2S)-2-[[(1R)-1-cyclopropyl-2-methoxyethyl]amino]-N-(2-methoxy-5-methylphenyl)-2-phenylacetamide
CID 97238931
(2R)-N-(2,5-dimethylphenyl)-2-(2-methoxyanilino)-2-phenylacetamide
CID 9345391
(2S)-N-(2,5-dimethylphenyl)-2-[(4-methylphenyl)methylamino]-2-phenylacetamide
CID 7928830
[(1R)-2-(2-methoxy-5-methylanilino)-2-oxo-1-phenylethyl] 2-methoxyacetate
CID 8015324
N-[1-(2-methoxy-5-methylanilino)-1-oxopropan-2-yl]thiophene-2-carboxamide
CID 46756520
2-methoxy-4-methyl-N-(thiophen-2-ylmethyl)aniline
CID 60932472
(2S)-N-(2-methoxy-5-methylphenyl)-2-phenylsulfanylpropanamide
CID 26733753

Frequently Asked Questions

What is the IUPAC name of (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide?
The IUPAC name of (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide (CID 8512914) is (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide.
What is the SMILES notation for (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide?
The canonical SMILES for (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide is COc1ccc(C)cc1NC(=O)[C@H](NCc1cccs1)c1ccccc1.
What is the InChIKey of (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide?
The InChIKey is RFSZZHAMOCZYAR-HXUWFJFHSA-N. The full InChI is InChI=1S/C21H22N2O2S/c1-15-10-11-19(25-2)18(13-15)23-21(24)20(16-7-4-3-5-8-16)22-14-17-9-6-12-26-17/h3-13,20,22H,14H2,1-2H3,(H,23,24)/t20-/m1/s1.
What are the key properties of (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide?
(2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide has a molecular weight of 366.49 g/mol, XLogP of 4.53, 7 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-N-(2-methoxy-5-methylphenyl)-2-phenyl-2-(thiophen-2-ylmethylamino)acetamide is sourced from PubChem (CID 8512914), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).