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Cyclizine

C18H22N2 — CID 6726

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Data last refreshed: (MolForge compound catalog, from PubChem)

IUPAC1-benzhydryl-4-methylpiperazine
SMILESCN1CCN(C(c2ccccc2)c2ccccc2)CC1
InChIInChI=1S/C18H22N2/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18H,12-15H2,1H3
InChIKeyUVKZSORBKUEBAZ-UHFFFAOYSA-N
MW266.39 g/mol
LogP3.02
Rot. Bonds3

About Cyclizine

Cyclizine (PubChem CID 6726) has the molecular formula C18H22N2 and a molecular weight of 266.39 g/mol. Its IUPAC name is 1-benzhydryl-4-methylpiperazine.

Molecular Properties

Compound NameCyclizine
PubChem CID6726
Molecular FormulaC18H22N2
Molecular Weight266.39 g/mol
Exact Mass266.18
IUPAC Name1-benzhydryl-4-methylpiperazine
SMILESCN1CCN(C(c2ccccc2)c2ccccc2)CC1
InChIInChI=1S/C18H22N2/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18H,12-15H2,1H3
InChIKeyUVKZSORBKUEBAZ-UHFFFAOYSA-N
XLogP3.02
TPSA6.48 Ų
H-Bond Donors
H-Bond Acceptors2
Rotatable Bonds3
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500266.39
LogP ≤ 53.02
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 102

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Related Compounds

1-[(4-fluorophenyl)-phenylmethyl]-4-methylpiperazine
CID 67474730
1-[(S)-(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane
CID 5393145
1-benzhydryl-4-propan-2-ylpiperazine;2-methylpropane
CID 164924895
1-methyl-4-[(1-methylimidazol-2-yl)-phenylmethyl]piperazine
CID 12063609
1-(4-benzhydrylpiperazin-1-yl)ethanamine
CID 68974612
1-(1-benzhydrylazetidin-3-yl)-4-methylpiperazine;ethane
CID 90779796
1-[bis(4-chlorophenyl)methyl]-4-methylpiperazine;dihydrochloride
CID 3065514
1-benzhydryl-4-ethylpiperazine;ethane
CID 156743025
1-benzhydryl-4-butylpiperazine
CID 13416419
4-(4-benzhydrylpiperazin-1-yl)butan-2-amine
CID 71433044
1-benzhydryl-4-(2-piperidin-1-ylethyl)piperazine
CID 71411855
2-(4-methylpiperazin-1-yl)-1-phenylpropan-1-amine
CID 16786190

Frequently Asked Questions

What is the IUPAC name of Cyclizine?
The IUPAC name of Cyclizine (CID 6726) is 1-benzhydryl-4-methylpiperazine.
What is the SMILES notation for Cyclizine?
The canonical SMILES for Cyclizine is CN1CCN(C(c2ccccc2)c2ccccc2)CC1.
What is the InChIKey of Cyclizine?
The InChIKey is UVKZSORBKUEBAZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H22N2/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18H,12-15H2,1H3.
What are the key properties of Cyclizine?
Cyclizine has a molecular weight of 266.39 g/mol, XLogP of 3.02, 3 rotatable bonds, 0 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for Cyclizine is sourced from PubChem (CID 6726), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

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