Fluocinolonacetonid

Name: Fluocinolonacetonid — Molecular Data
Creator: MolForge
License: https://creativecommons.org/publicdomain/zero/1.0/

C₂₄H₃₀F₂O₆ — CID 6215

💊View drug profile → fluocinolone acetonide

Data last refreshed: 2026-04-14 (MolForge compound catalog, from PubChem)

IUPAC(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

SMILESCC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

InChIInChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChIKeyFEBLZLNTKCEFIT-VSXGLTOVSA-N

MW452.49 g/mol

LogP2.37

Rot. Bonds2

About Fluocinolonacetonid

Fluocinolonacetonid (PubChem CID 6215) has the molecular formula C₂₄H₃₀F₂O₆ and a molecular weight of 452.49 g/mol. Its IUPAC name is (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one.

Molecular Properties

Compound Name	Fluocinolonacetonid
PubChem CID	6215
Molecular Formula	C₂₄H₃₀F₂O₆
Molecular Weight	452.49 g/mol
Exact Mass	452.20
IUPAC Name	(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
SMILES	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
InChI	InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChIKey	FEBLZLNTKCEFIT-VSXGLTOVSA-N
XLogP	2.37
TPSA	93.06 Å²
H-Bond Donors	2
H-Bond Acceptors	6
Rotatable Bonds	2
Heavy Atoms	32
Complexity	—

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	452.49
LogP ≤ 5	2.37
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	6

Related Compounds

Frequently Asked Questions

What is the IUPAC name of Fluocinolonacetonid?

The IUPAC name of Fluocinolonacetonid (CID 6215) is (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one.

What is the SMILES notation for Fluocinolonacetonid?

The canonical SMILES for Fluocinolonacetonid is CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1.

What is the InChIKey of Fluocinolonacetonid?

The InChIKey is FEBLZLNTKCEFIT-VSXGLTOVSA-N. The full InChI is InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1.

What are the key properties of Fluocinolonacetonid?

Fluocinolonacetonid has a molecular weight of 452.49 g/mol, XLogP of 2.37, 2 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for Fluocinolonacetonid is sourced from PubChem (CID 6215), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Browse: Molecules: F · all molecules A–Z · drugs A–Z · protein targets A–Z.

Sources

PubChem CID 6215 — identifiers, structure, computed properties (public domain)
DrugCentral drug card 1204 — approved-drug record (CC BY-SA 4.0)

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