Sodium/mannose cotransporter SLC5A10 (SLC5A10)
Homo sapiens — UniProt A0PJK1
Data last refreshed: (UniProt release unknown)
Key facts
Sodium/mannose cotransporter SLC5A10 (SLC5A10) is a protein from Homo sapiens identified by UniProt accession A0PJK1, 596 residues long. MolForge cross-references it against 1 known binders and 98 disease associations.
- UniProt accession: A0PJK1; gene symbol SLC5A10.
- Organism: Homo sapiens.
- Length: 596 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): 1,5 anhydroglucitol measurement, familial idiopathic steroid-resistant nephrotic syndrome and CIDEC-related familial partial lipodystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium/mannose cotransporter SLC5A10 |
|---|---|
| UniProt accession | A0PJK1 |
| Gene | SLC5A10 |
| Organism | Homo sapiens |
| Length | 596 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- 1,5 anhydroglucitol measurement · score 0.25
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.05
- CIDEC-related familial partial lipodystrophy · score 0.05
- nephrotic syndrome · score 0.05
- glycogen storage disease VI · score 0.05
- PLIN1-related familial partial lipodystrophy · score 0.05
- lymphocyte count · score 0.04
- acquired partial lipodystrophy · score 0.04
- neonatal intrahepatic cholestasis due to citrin deficiency · score 0.04
- congenital nephrotic syndrome, Finnish type · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A0PJK1-F1 | alphafold | PREDICTED | 87.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A0PJK1.
Amino-acid sequence (596 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC5A10?
The strongest Open Targets associations for SLC5A10 are 1,5 anhydroglucitol measurement, familial idiopathic steroid-resistant nephrotic syndrome, CIDEC-related familial partial lipodystrophy, nephrotic syndrome and glycogen storage disease VI.
How long is the SLC5A10 protein?
The Homo sapiens SLC5A10 protein (UniProt A0PJK1) is 596 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A0PJK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A0PJK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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