Anoctamin-9 (ANO9)
Homo sapiens — UniProt A1A5B4
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-9 (ANO9) is a protein from Homo sapiens identified by UniProt accession A1A5B4, 782 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: A1A5B4; gene symbol ANO9.
- Organism: Homo sapiens.
- Length: 782 amino acids.
- Top disease associations (Open Targets): COVID-19, nevus count and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-9 |
|---|---|
| UniProt accession | A1A5B4 |
| Gene | ANO9 |
| Organism | Homo sapiens |
| Length | 782 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.37
- nevus count · score 0.22
- cutaneous melanoma · score 0.22
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.12
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- colorectal carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A1A5B4-F1 | alphafold | PREDICTED | 80.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A1A5B4.
Amino-acid sequence (782 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO9?
The strongest Open Targets associations for ANO9 are COVID-19, nevus count, cutaneous melanoma, glioblastoma multiforme and breast adenocarcinoma.
How long is the ANO9 protein?
The Homo sapiens ANO9 protein (UniProt A1A5B4) is 782 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A1A5B4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A1A5B4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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