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Solute carrier family 22 member 23 (SLC22A23)

Homo sapiens — UniProt A1A5C7

Gene: SLC22A23Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier family 22 member 23 (SLC22A23) is a protein from Homo sapiens identified by UniProt accession A1A5C7, 686 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

  • UniProt accession: A1A5C7; gene symbol SLC22A23.
  • Organism: Homo sapiens.
  • Length: 686 amino acids.
  • Top disease associations (Open Targets): Red cell distribution width, mean platelet volume and self reported educational attainment.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier family 22 member 23
UniProt accessionA1A5C7
GeneSLC22A23
OrganismHomo sapiens
Length686 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (55)

Diseases linked to this target (Open Targets).

  • Red cell distribution width · score 0.52
  • mean platelet volume · score 0.50
  • self reported educational attainment · score 0.46
  • intelligence · score 0.45
  • electrocardiography · score 0.43
  • Crohn's disease · score 0.40
  • mean corpuscular hemoglobin · score 0.37
  • mean corpuscular hemoglobin concentration · score 0.34
  • hemoglobin A1 measurement · score 0.33
  • HbA1c measurement · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A1A5C7-F1alphafoldPREDICTED72.18—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A1A5C7.

Amino-acid sequence (686 residues)

MAIDRRREAA GGGPGRQPAP AEENGSLPPG DAAASAPLGG RAGPGGGAEI QPLPPLHPGG GPHPSCCSAA AAPSLLLLDY DGSVLPFLGG LGGGYQKTLV LLTWIPALFI GFSQFSDSFL LDQPNFWCRG AGKGTELAGV TTTGRGGDMG NWTSLPTTPF ATAPWEAAGN RSNSSGADGG DTPPLPSPPD KGDNASNCDC RAWDYGIRAG LVQNVVSKWD LVCDNAWKVH IAKFSLLVGL IFGYLITGCI ADWVGRRPVL LFSIIFILIF GLTVALSVNV TMFSTLRFFE GFCLAGIILT LYALRIELCP PGKRFMITMV ASFVAMAGQF LMPGLAALCR DWQVLQALII CPFLLMLLYW SIFPESLRWL MATQQFESAK RLILHFTQKN RMNPEGDIKG VIPELEKELS RRPKKVCIVK VVGTRNLWKN IVVLCVNSLT GYGIHHCFAR SMMGHEVKVP LLENFYADYY TTASIALVSC LAMCVVVRFL GRRGGLLLFM ILTALASLLQ LGLLNLIGKY SQHPDSGMSD SVKDKFSIAF SIVGMFASHA VGSLSVFFCA EITPTVIRCG GLGLVLASAG FGMLTAPIIE LHNQKGYFLH HIIFACCTLI CIICILLLPE SRDQNLPENI SNGEHYTRQP LLPHKKGEQP LLLTNAELKD YSGLHDAAAA GDTLPEGATA NGMKAM

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC22A23?

The strongest Open Targets associations for SLC22A23 are Red cell distribution width, mean platelet volume, self reported educational attainment, intelligence and electrocardiography.

How long is the SLC22A23 protein?

The Homo sapiens SLC22A23 protein (UniProt A1A5C7) is 686 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA1A5C7
GeneSLC22A23
OrganismHomo sapiens
Length686
Binders0
Diseases55
View on UniProt