BICD family-like cargo adapter 2 (BICDL2)
Homo sapiens — UniProt A1A5D9
Data last refreshed: (UniProt release unknown)
Key facts
BICD family-like cargo adapter 2 (BICDL2) is a protein from Homo sapiens identified by UniProt accession A1A5D9, 508 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: A1A5D9; gene symbol BICDL2.
- Organism: Homo sapiens.
- Length: 508 amino acids.
- Top disease associations (Open Targets): brain measurement, kidney disease and Senior-Boichis syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BICD family-like cargo adapter 2 |
|---|---|
| UniProt accession | A1A5D9 |
| Gene | BICDL2 |
| Organism | Homo sapiens |
| Length | 508 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- brain measurement · score 0.07
- kidney disease · score 0.05
- Senior-Boichis syndrome · score 0.04
- hepatorenocardiac degenerative fibrosis · score 0.04
- congenital nonspherocytic hemolytic anemia · score 0.04
- glycoprotein storage disease · score 0.04
- hemoglobin H disease · score 0.04
- pancreatic adenocarcinoma · score 0.04
- Recurrent infections-myelofibrosis-nephromegaly syndrome · score 0.04
- dominant beta-thalassemia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A1A5D9-F1 | alphafold | PREDICTED | 79.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A1A5D9.
Amino-acid sequence (508 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BICDL2?
The strongest Open Targets associations for BICDL2 are brain measurement, kidney disease, Senior-Boichis syndrome, hepatorenocardiac degenerative fibrosis and congenital nonspherocytic hemolytic anemia.
How long is the BICDL2 protein?
The Homo sapiens BICDL2 protein (UniProt A1A5D9) is 508 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A1A5D9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A1A5D9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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