Very long chain fatty acid elongase 7 (ELOVL7)
Homo sapiens — UniProt A1L3X0
Data last refreshed: (UniProt release unknown)
Key facts
Very long chain fatty acid elongase 7 (ELOVL7) is a protein from Homo sapiens identified by UniProt accession A1L3X0, 281 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: A1L3X0; gene symbol ELOVL7.
- Organism: Homo sapiens.
- Length: 281 amino acids.
- Top disease associations (Open Targets): mean platelet volume, self reported educational attainment and cortical surface area measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Very long chain fatty acid elongase 7 |
|---|---|
| UniProt accession | A1L3X0 |
| Gene | ELOVL7 |
| Organism | Homo sapiens |
| Length | 281 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.69
- self reported educational attainment · score 0.49
- cortical surface area measurement · score 0.39
- mathematical ability · score 0.37
- Parkinson disease · score 0.37
- brain volume measurement · score 0.35
- smoking initiation · score 0.34
- neurodegenerative disease · score 0.33
- cognitive function measurement · score 0.33
- smoking status measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A1L3X0-F1 | alphafold | PREDICTED | 89.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A1L3X0.
Amino-acid sequence (281 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELOVL7?
The strongest Open Targets associations for ELOVL7 are mean platelet volume, self reported educational attainment, cortical surface area measurement, mathematical ability and Parkinson disease.
How long is the ELOVL7 protein?
The Homo sapiens ELOVL7 protein (UniProt A1L3X0) is 281 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A1L3X0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A1L3X0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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