Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (SSC5D)

Homo sapiens — UniProt A1L4H1

Gene: SSC5DHomo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (SSC5D) is a protein from Homo sapiens identified by UniProt accession A1L4H1, 1573 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

UniProt accession: A1L4H1; gene symbol SSC5D.
Organism: Homo sapiens.
Length: 1573 amino acids.
Top disease associations (Open Targets): lean body mass, BMI-adjusted waist-hip ratio and waist-hip ratio.
3D structure: AlphaFold model available.

Target properties

Protein name	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D
UniProt accession	A1L4H1
Gene	SSC5D
Organism	Homo sapiens
Length	1573 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

lean body mass · score 0.35
BMI-adjusted waist-hip ratio · score 0.25
waist-hip ratio · score 0.23
base metabolic rate measurement · score 0.16
vital capacity · score 0.16
fat body mass · score 0.10
whole body water mass · score 0.09
macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.07
thrombocytopenia 4 · score 0.07
autosomal dominant macrothrombocytopenia · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L4H1-F1	alphafold	PREDICTED	52.33	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A1L4H1.

Amino-acid sequence (1573 residues)

MRVLACLLAA LVGIQAVERL RLADGPHGCA GRLEVWHGGR WGTVCDDGWD LRDAAVACRQ LGCGGALAAP GGAFFGEGAG PVWLSELACR GNEGQLGLCH HRGWKAHICS HEEDAGVVCA GQRVANSRDD STSPLDGAPW PGLLLELSPS TEEPLVTHAP RPAGNPQNAS RKKSPRPKQA KSTRAPLLTT GAPRQERLRL VSGPHRCAGR LEVWHGGRWG TVCDDGWDLR DAAVACRELG CGGALAAPGG ARFGPGAGPV WMDDVGCGGG EQALRDCPRS PWGRSNCDHS EDAGLVCTGP APRLRLADGP HGCAGRLEVW HGGRWGSVCD DAWDLRDAAV ACRELGCGGA LAAPGGAFFG EGSGPIILDD LRCRGNETAL RFCPARPWGQ HDCHHREDAG AVCDGMPLGY VPPTAPTDSN NSTPREAASR PPSTMTSQAP GTAGVSPPPA SPTVLWEPGP EAGSPQLRLV AGPSKCSGRL EVWHDQRWGT VCDDSWDMRD SAVVCRELGC GGPQQPDPAA GRFGWGAGPI WLDDVGCVGT EASLSDCPAA PWGKHNCAHN EDVGVTCTGP PGLDSISDPF SWSWIPGLGR DRDAWLPGEL ATKPSASVTA SVLEKTTTKA PGKMPKSTKK WVTKNAKRPT TQPPVMPTTK HSRAQSPPDL TSQTTAALTT EASRRPTSEF TRRPTTEAPQ RWTSHTTATL TPQAPRERTT KTMAMLTTQG PQEMTSESTI KSIPQASLEP SAEIPEGSPE SPKDPAPSPS VSTTGESGLF RVRLADGPNR CAGRLEVWHA GRWGTVCDDN WDLRDATVAC WELGCGKVRP RVGKTHYGPG TGPIWLDDMG CKGSEASLSD CPSGAWGKHN CDHEEDVGLT CTGYTDYDDY PPWTWDPTSR EDLAKGTTTA GVPGHTLPWR TTRRPGSSSP AIRRLPDTGS KDGYKLPWTW DTPSGRGLAE GTPTAGKLGP TLGAGTTRSP GSPPTLRVHG DTGSPRKPWP ERRPPRPAAT RTAPPTPSPG PSASPGPPGP ALTSDSSREL TPHSALTSEA TSDAPDTSPP TPDPASRTNP DLILTSPDFA LSTPDSSVVP ALTPEPSPTP LPTLPKELTS DPSTPSEVTS LSPTSEQVPE SDTTPDLDTT PYSSTVSEYS RSPDPSPSPH PTTTPDPTMA PDPITTLNPT VTPHFPTTPH PTTTPHPTTI THSTMIPDPT TTPQPFTTIT HSTMIPDPTT TPQPFTTMQP TTTPHSTTPH PTTTPHPTTI THSTMIPDPT TTPQPFTTMQ PTTMPHPTTT PHPTTTPHPT TTPHPTTTPH PTMTPDPTTT PYPTTTPDPT TTPHPTTPDP SSTPVITTVS LPTSLGTELS SPTLAPTVKP SLHPQLTFTA PAPHTSTSQI PTLEPSPALE SSPSRSSTAT SMDPLSTEDF KPPRSQSPNL TPPPTHTPHS ASDLTVSPDP LLSPTAHPLD HPPLDPLTLG PTPGQSPGPH GPCVAPTPPV RVMACEPPAL VELVAAVRDV GGQLQRLTQV VEQERQERQA LLLGLTQLVE AARGLGQLGE AVKRLAEMAW TTSMPAPTTT TPEEEERPLR GDV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SSC5D?

The strongest Open Targets associations for SSC5D are lean body mass, BMI-adjusted waist-hip ratio, waist-hip ratio, base metabolic rate measurement and vital capacity.

How long is the SSC5D protein?

The Homo sapiens SSC5D protein (UniProt A1L4H1) is 1573 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB A1L4H1 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB A1L4H1 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

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