Small integral membrane protein 30 (SMIM30)
Homo sapiens — UniProt A4D0T7
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 30 (SMIM30) is a protein from Homo sapiens identified by UniProt accession A4D0T7, 59 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: A4D0T7; gene symbol SMIM30.
- Organism: Homo sapiens.
- Length: 59 amino acids.
- Top disease associations (Open Targets): eosinophil count, eosinophil percentage of leukocytes and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 30 |
|---|---|
| UniProt accession | A4D0T7 |
| Gene | SMIM30 |
| Organism | Homo sapiens |
| Length | 59 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.46
- eosinophil percentage of leukocytes · score 0.39
- body mass index · score 0.31
- neutrophil percentage of granulocytes · score 0.30
- eosinophil percentage of granulocytes · score 0.30
- sum of eosinophil and basophil counts · score 0.30
- PHF-tau measurement · score 0.28
- body fat percentage · score 0.26
- lean body mass · score 0.25
- fat body mass · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A4D0T7-F1 | alphafold | PREDICTED | 85.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A4D0T7.
Amino-acid sequence (59 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM30?
The strongest Open Targets associations for SMIM30 are eosinophil count, eosinophil percentage of leukocytes, body mass index, neutrophil percentage of granulocytes and eosinophil percentage of granulocytes.
How long is the SMIM30 protein?
The Homo sapiens SMIM30 protein (UniProt A4D0T7) is 59 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A4D0T7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A4D0T7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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