Zinc finger protein 804B (ZNF804B)
Homo sapiens — UniProt A4D1E1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 804B (ZNF804B) is a protein from Homo sapiens identified by UniProt accession A4D1E1, 1349 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: A4D1E1; gene symbol ZNF804B.
- Organism: Homo sapiens.
- Length: 1349 amino acids.
- Top disease associations (Open Targets): breast milk measurement, parental genotype effect measurement and fatty acid measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 804B |
|---|---|
| UniProt accession | A4D1E1 |
| Gene | ZNF804B |
| Organism | Homo sapiens |
| Length | 1349 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- breast milk measurement · score 0.37
- parental genotype effect measurement · score 0.37
- fatty acid measurement · score 0.37
- restless legs syndrome · score 0.32
- neurodegenerative disease · score 0.32
- memory performance · score 0.31
- insomnia measurement · score 0.29
- smoking status measurement · score 0.24
- pancreatic adenocarcinoma · score 0.14
- metabolite measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A4D1E1-F1 | alphafold | PREDICTED | 42.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A4D1E1.
Amino-acid sequence (1349 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF804B?
The strongest Open Targets associations for ZNF804B are breast milk measurement, parental genotype effect measurement, fatty acid measurement, restless legs syndrome and neurodegenerative disease.
How long is the ZNF804B protein?
The Homo sapiens ZNF804B protein (UniProt A4D1E1) is 1349 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A4D1E1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A4D1E1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.