Ras-related protein Rab-19 (RAB19)
Homo sapiens — UniProt A4D1S5
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-19 (RAB19) is a protein from Homo sapiens identified by UniProt accession A4D1S5, 217 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: A4D1S5; gene symbol RAB19.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): age at first sexual intercourse measurement, creatinine measurement and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-19 |
|---|---|
| UniProt accession | A4D1S5 |
| Gene | RAB19 |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- age at first sexual intercourse measurement · score 0.43
- creatinine measurement · score 0.25
- attention deficit hyperactivity disorder · score 0.23
- substance abuse · score 0.23
- antisocial behaviour measurement · score 0.23
- glomerular filtration rate · score 0.22
- refractive error measurement · score 0.12
- non-syndromic syndactyly · score 0.12
- metabolite measurement · score 0.09
- cystatin C measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A4D1S5-F1 | alphafold | PREDICTED | 82.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A4D1S5.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB19?
The strongest Open Targets associations for RAB19 are age at first sexual intercourse measurement, creatinine measurement, attention deficit hyperactivity disorder, substance abuse and antisocial behaviour measurement.
How long is the RAB19 protein?
The Homo sapiens RAB19 protein (UniProt A4D1S5) is 217 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A4D1S5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A4D1S5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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