POTE ankyrin domain family member F (POTEF)
Homo sapiens — UniProt A5A3E0
Data last refreshed: (UniProt release unknown)
Key facts
POTE ankyrin domain family member F (POTEF) is a protein from Homo sapiens identified by UniProt accession A5A3E0, 1075 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: A5A3E0; gene symbol POTEF.
- Organism: Homo sapiens.
- Length: 1075 amino acids.
- Top disease associations (Open Targets): blood protein measurement, DNA methylation and gastric carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POTE ankyrin domain family member F |
|---|---|
| UniProt accession | A5A3E0 |
| Gene | POTEF |
| Organism | Homo sapiens |
| Length | 1075 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.02
- DNA methylation · score 0.02
- gastric carcinoma · score 0.02
- triple-negative breast cancer · score 0.01
- Ataxia-telangiectasia · score 0.01
- non-small cell lung carcinoma · score 0.01
- hepatocellular carcinoma · score 0.01
- neoplasm · score 0.00
- cancer · score 0.00
- chronic kidney disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A5A3E0-F1 | alphafold | PREDICTED | 70.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A5A3E0.
Amino-acid sequence (1075 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POTEF?
The strongest Open Targets associations for POTEF are blood protein measurement, DNA methylation, gastric carcinoma, triple-negative breast cancer and Ataxia-telangiectasia.
How long is the POTEF protein?
The Homo sapiens POTEF protein (UniProt A5A3E0) is 1075 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A5A3E0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A5A3E0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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