Fat storage-inducing transmembrane protein 1 (FITM1)
Homo sapiens — UniProt A5D6W6
Data last refreshed: (UniProt release unknown)
Key facts
Fat storage-inducing transmembrane protein 1 (FITM1) is a protein from Homo sapiens identified by UniProt accession A5D6W6, 292 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: A5D6W6; gene symbol FITM1.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, neoplasm and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fat storage-inducing transmembrane protein 1 |
|---|---|
| UniProt accession | A5D6W6 |
| Gene | FITM1 |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.06
- neoplasm · score 0.05
- body height · score 0.04
- pancreatic neoplasm · score 0.01
- chronic obstructive pulmonary disease · score 0.01
- cancer · score 0.01
- metabolic disease · score 0.00
- non-small cell lung carcinoma · score 0.00
- non-alcoholic fatty liver disease · score 0.00
- viral disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A5D6W6-F1 | alphafold | PREDICTED | 85.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A5D6W6.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FITM1?
The strongest Open Targets associations for FITM1 are hepatocellular carcinoma, neoplasm, body height, pancreatic neoplasm and chronic obstructive pulmonary disease.
How long is the FITM1 protein?
The Homo sapiens FITM1 protein (UniProt A5D6W6) is 292 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A5D6W6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A5D6W6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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