C-type lectin domain family 18 member A (CLEC18A)
Homo sapiens — UniProt A5D8T8
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 18 member A (CLEC18A) is a protein from Homo sapiens identified by UniProt accession A5D8T8, 446 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: A5D8T8; gene symbol CLEC18A.
- Organism: Homo sapiens.
- Length: 446 amino acids.
- Top disease associations (Open Targets): tobacco smoke exposure measurement, smoking status measurement and osteoarthritis, knee.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 18 member A |
|---|---|
| UniProt accession | A5D8T8 |
| Gene | CLEC18A |
| Organism | Homo sapiens |
| Length | 446 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- tobacco smoke exposure measurement · score 0.22
- smoking status measurement · score 0.16
- osteoarthritis, knee · score 0.15
- vital capacity · score 0.13
- alkaline phosphatase measurement · score 0.12
- grip strength measurement · score 0.12
- pulse pressure measurement · score 0.12
- systolic blood pressure · score 0.11
- amino acid measurement · score 0.10
- protein measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A5D8T8-F1 | alphafold | PREDICTED | 78.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A5D8T8.
Amino-acid sequence (446 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC18A?
The strongest Open Targets associations for CLEC18A are tobacco smoke exposure measurement, smoking status measurement, osteoarthritis, knee, vital capacity and alkaline phosphatase measurement.
How long is the CLEC18A protein?
The Homo sapiens CLEC18A protein (UniProt A5D8T8) is 446 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A5D8T8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A5D8T8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.