Outer dynein arm-docking complex subunit 3 (ODAD3)
Homo sapiens — UniProt A5D8V7
Data last refreshed: (UniProt release unknown)
Key facts
Outer dynein arm-docking complex subunit 3 (ODAD3) is a protein from Homo sapiens identified by UniProt accession A5D8V7, 595 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: A5D8V7; gene symbol ODAD3.
- Organism: Homo sapiens.
- Length: 595 amino acids.
- Top disease associations (Open Targets): primary ciliary dyskinesia, genetic disorder and Kartagener Syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Outer dynein arm-docking complex subunit 3 |
|---|---|
| UniProt accession | A5D8V7 |
| Gene | ODAD3 |
| Organism | Homo sapiens |
| Length | 595 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- primary ciliary dyskinesia · score 0.70
- genetic disorder · score 0.41
- Kartagener Syndrome · score 0.34
- polycystic liver disease 1 · score 0.16
- serum metabolite measurement · score 0.10
- antiphospholipid antibody measurement · score 0.06
- liver disease · score 0.06
- Heterotaxia · score 0.06
- heterotaxy, visceral, 9, autosomal, with male infertility · score 0.05
- ossification of the posterior longitudinal ligament of the spine · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A5D8V7-F1 | alphafold | PREDICTED | 77.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A5D8V7.
Amino-acid sequence (595 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ODAD3?
The strongest Open Targets associations for ODAD3 are primary ciliary dyskinesia, genetic disorder, Kartagener Syndrome, polycystic liver disease 1 and serum metabolite measurement.
How long is the ODAD3 protein?
The Homo sapiens ODAD3 protein (UniProt A5D8V7) is 595 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A5D8V7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A5D8V7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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