Cadherin-related family member 4 (CDHR4)
Homo sapiens — UniProt A6H8M9
Data last refreshed: (UniProt release unknown)
Key facts
Cadherin-related family member 4 (CDHR4) is a protein from Homo sapiens identified by UniProt accession A6H8M9, 788 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: A6H8M9; gene symbol CDHR4.
- Organism: Homo sapiens.
- Length: 788 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, diastolic blood pressure and total blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cadherin-related family member 4 |
|---|---|
| UniProt accession | A6H8M9 |
| Gene | CDHR4 |
| Organism | Homo sapiens |
| Length | 788 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.28
- diastolic blood pressure · score 0.20
- total blood protein measurement · score 0.16
- erythrocyte count · score 0.15
- systolic blood pressure · score 0.14
- red blood cell density measurement · score 0.13
- hematocrit · score 0.12
- FEV/FVC ratio · score 0.12
- heel bone mineral density · score 0.11
- cognitive function measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6H8M9-F1 | alphafold | PREDICTED | 78.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6H8M9.
Amino-acid sequence (788 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDHR4?
The strongest Open Targets associations for CDHR4 are Red cell distribution width, diastolic blood pressure, total blood protein measurement, erythrocyte count and systolic blood pressure.
How long is the CDHR4 protein?
The Homo sapiens CDHR4 protein (UniProt A6H8M9) is 788 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6H8M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6H8M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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