Uncharacterized protein C2orf78 (C2orf78)
Homo sapiens — UniProt A6NCI8
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C2orf78 (C2orf78) is a protein from Homo sapiens identified by UniProt accession A6NCI8, 922 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: A6NCI8; gene symbol C2orf78.
- Organism: Homo sapiens.
- Length: 922 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum metabolite measurement and colorectal adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C2orf78 |
|---|---|
| UniProt accession | A6NCI8 |
| Gene | C2orf78 |
| Organism | Homo sapiens |
| Length | 922 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- serum metabolite measurement · score 0.13
- colorectal adenocarcinoma · score 0.04
- glomerular filtration rate · score 0.03
- macrovascular complications of diabetes · score 0.03
- protein measurement · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- diabetes mellitus · score 0.00
- Obesity · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NCI8-F1 | alphafold | PREDICTED | 42.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NCI8.
Amino-acid sequence (922 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2orf78?
The strongest Open Targets associations for C2orf78 are neurodegenerative disease, serum metabolite measurement, colorectal adenocarcinoma, glomerular filtration rate and macrovascular complications of diabetes.
How long is the C2orf78 protein?
The Homo sapiens C2orf78 protein (UniProt A6NCI8) is 922 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NCI8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NCI8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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