Tektin bundle-interacting protein 1 (TEKTIP1)
Homo sapiens — UniProt A6NCJ1
Data last refreshed: (UniProt release unknown)
Key facts
Tektin bundle-interacting protein 1 (TEKTIP1) is a protein from Homo sapiens identified by UniProt accession A6NCJ1, 209 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: A6NCJ1; gene symbol TEKTIP1.
- Organism: Homo sapiens.
- Length: 209 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, skin pigmentation measurement and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tektin bundle-interacting protein 1 |
|---|---|
| UniProt accession | A6NCJ1 |
| Gene | TEKTIP1 |
| Organism | Homo sapiens |
| Length | 209 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.13
- skin pigmentation measurement · score 0.11
- cutaneous melanoma · score 0.09
- facial pigmentation measurement · score 0.09
- uric acid measurement · score 0.08
- reticulocyte measurement · score 0.08
- reticulocyte count · score 0.07
- blood protein measurement · score 0.07
- aspartate aminotransferase measurement · score 0.05
- hair color · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NCJ1-F1 | alphafold | PREDICTED | 41.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NCJ1.
Amino-acid sequence (209 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TEKTIP1?
The strongest Open Targets associations for TEKTIP1 are Red cell distribution width, skin pigmentation measurement, cutaneous melanoma, facial pigmentation measurement and uric acid measurement.
How long is the TEKTIP1 protein?
The Homo sapiens TEKTIP1 protein (UniProt A6NCJ1) is 209 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NCJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NCJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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