Dynein regulatory complex subunit like-11 (DRC11L)
Homo sapiens — UniProt A6NCM1
Data last refreshed: (UniProt release unknown)
Key facts
Dynein regulatory complex subunit like-11 (DRC11L) is a protein from Homo sapiens identified by UniProt accession A6NCM1, 818 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: A6NCM1; gene symbol DRC11L.
- Organism: Homo sapiens.
- Length: 818 amino acids.
- Top disease associations (Open Targets): viral load, neuroimaging measurement and cortical surface area measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynein regulatory complex subunit like-11 |
|---|---|
| UniProt accession | A6NCM1 |
| Gene | DRC11L |
| Organism | Homo sapiens |
| Length | 818 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- viral load · score 0.16
- neuroimaging measurement · score 0.14
- cortical surface area measurement · score 0.14
- SAPHO syndrome · score 0.06
- red blood cell density measurement · score 0.02
- hematocrit · score 0.02
- colorectal cancer · score 0.00
- Crohn's disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NCM1-F1 | alphafold | PREDICTED | 81.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NCM1.
Amino-acid sequence (818 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DRC11L?
The strongest Open Targets associations for DRC11L are viral load, neuroimaging measurement, cortical surface area measurement, SAPHO syndrome and red blood cell density measurement.
How long is the DRC11L protein?
The Homo sapiens DRC11L protein (UniProt A6NCM1) is 818 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NCM1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NCM1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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