Uncharacterized protein C2orf72 (C2orf72)
Homo sapiens — UniProt A6NCS6
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C2orf72 (C2orf72) is a protein from Homo sapiens identified by UniProt accession A6NCS6, 295 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: A6NCS6; gene symbol C2orf72.
- Organism: Homo sapiens.
- Length: 295 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, refractive error measurement and Barrett's esophagus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C2orf72 |
|---|---|
| UniProt accession | A6NCS6 |
| Gene | C2orf72 |
| Organism | Homo sapiens |
| Length | 295 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- refractive error measurement · score 0.11
- Barrett's esophagus · score 0.05
- creatinine measurement · score 0.05
- breast carcinoma · score 0.03
- esophageal adenocarcinoma · score 0.03
- Acute hepatic failure · score 0.01
- medulloblastoma · score 0.01
- psoriasis · score 0.01
- uterine leiomyosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NCS6-F1 | alphafold | PREDICTED | 65.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NCS6.
Amino-acid sequence (295 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2orf72?
The strongest Open Targets associations for C2orf72 are neurodegenerative disease, refractive error measurement, Barrett's esophagus, creatinine measurement and breast carcinoma.
How long is the C2orf72 protein?
The Homo sapiens C2orf72 protein (UniProt A6NCS6) is 295 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NCS6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NCS6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.