Paralemmin-3 (PALM3)
Homo sapiens — UniProt A6NDB9
Data last refreshed: (UniProt release unknown)
Key facts
Paralemmin-3 (PALM3) is a protein from Homo sapiens identified by UniProt accession A6NDB9, 673 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: A6NDB9; gene symbol PALM3.
- Organism: Homo sapiens.
- Length: 673 amino acids.
- Top disease associations (Open Targets): calcium measurement, sex hormone-binding globulin measurement and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Paralemmin-3 |
|---|---|
| UniProt accession | A6NDB9 |
| Gene | PALM3 |
| Organism | Homo sapiens |
| Length | 673 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.31
- sex hormone-binding globulin measurement · score 0.30
- serum gamma-glutamyl transferase measurement · score 0.30
- testosterone measurement · score 0.21
- low density lipoprotein cholesterol measurement · score 0.19
- blood phosphate measurement · score 0.18
- mean corpuscular volume · score 0.12
- sensorineural hearing loss · score 0.12
- creatinine measurement · score 0.11
- cystatin C measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NDB9-F1 | alphafold | PREDICTED | 50.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NDB9.
Amino-acid sequence (673 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PALM3?
The strongest Open Targets associations for PALM3 are calcium measurement, sex hormone-binding globulin measurement, serum gamma-glutamyl transferase measurement, testosterone measurement and low density lipoprotein cholesterol measurement.
How long is the PALM3 protein?
The Homo sapiens PALM3 protein (UniProt A6NDB9) is 673 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NDB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NDB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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