G antigen 12H (GAGE12H)

Homo sapiens — UniProt A6NDE8

Gene: GAGE12HHomo sapiensSwissProt reviewed

About G antigen 12H

G antigen 12H (GAGE12H) is a protein from Homo sapiens identified by UniProt accession A6NDE8, 117 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein nameG antigen 12H
UniProt accessionA6NDE8
GeneGAGE12H
OrganismHomo sapiens
Length117 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (2)

Diseases linked to this target (Open Targets).

  • cancer · score 0.01
  • neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NDE8-F1alphafoldPREDICTED63.21—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NDE8.

Amino-acid sequence (117 residues)

MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQC QDPAAAQKGE DEGASAGQGP KPEAHSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEKQSQC

Explore G antigen 12H with MolForge

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Quick facts

UniProtA6NDE8
GeneGAGE12H
OrganismHomo sapiens
Length117
Binders0
Diseases2
View on UniProt