RAB7A-interacting MON1-CCZ1 complex subunit 1 (RIMOC1)
Homo sapiens — UniProt A6NDU8
Data last refreshed: (UniProt release unknown)
Key facts
RAB7A-interacting MON1-CCZ1 complex subunit 1 (RIMOC1) is a protein from Homo sapiens identified by UniProt accession A6NDU8, 294 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: A6NDU8; gene symbol RIMOC1.
- Organism: Homo sapiens.
- Length: 294 amino acids.
- Top disease associations (Open Targets): Ketonuria, Familial exudative vitreoretinopathy and X-linked retinal dysplasia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RAB7A-interacting MON1-CCZ1 complex subunit 1 |
|---|---|
| UniProt accession | A6NDU8 |
| Gene | RIMOC1 |
| Organism | Homo sapiens |
| Length | 294 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- Ketonuria · score 0.07
- Familial exudative vitreoretinopathy · score 0.06
- X-linked retinal dysplasia · score 0.05
- exudative vitreoretinopathy 2, X-linked · score 0.03
- proliferative vitreoretinopathy · score 0.03
- hyperostosis corticalis generalisata · score 0.03
- heel bone mineral density · score 0.03
- Ataxia-telangiectasia · score 0.01
- hepatocellular carcinoma · score 0.00
- Thalassemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NDU8-F1 | alphafold | PREDICTED | 85.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NDU8.
Amino-acid sequence (294 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIMOC1?
The strongest Open Targets associations for RIMOC1 are Ketonuria, Familial exudative vitreoretinopathy, X-linked retinal dysplasia, exudative vitreoretinopathy 2, X-linked and proliferative vitreoretinopathy.
How long is the RIMOC1 protein?
The Homo sapiens RIMOC1 protein (UniProt A6NDU8) is 294 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NDU8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NDU8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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