Ankyrin repeat domain-containing protein SOWAHB (SOWAHB)
Homo sapiens — UniProt A6NEL2
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein SOWAHB (SOWAHB) is a protein from Homo sapiens identified by UniProt accession A6NEL2, 793 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: A6NEL2; gene symbol SOWAHB.
- Organism: Homo sapiens.
- Length: 793 amino acids.
- Top disease associations (Open Targets): body height, emphysema pattern measurement and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein SOWAHB |
|---|---|
| UniProt accession | A6NEL2 |
| Gene | SOWAHB |
| Organism | Homo sapiens |
| Length | 793 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- body height · score 0.44
- emphysema pattern measurement · score 0.29
- vital capacity · score 0.12
- cortical thickness · score 0.06
- central nervous system cancer · score 0.04
- isolated spina bifida · score 0.04
- anencephaly 1 · score 0.04
- spina bifida-hypospadias syndrome · score 0.04
- gut microbiome measurement · score 0.04
- taxonomic microbiome measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NEL2-F1 | alphafold | PREDICTED | 54.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NEL2.
Amino-acid sequence (793 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOWAHB?
The strongest Open Targets associations for SOWAHB are body height, emphysema pattern measurement, vital capacity, cortical thickness and central nervous system cancer.
How long is the SOWAHB protein?
The Homo sapiens SOWAHB protein (UniProt A6NEL2) is 793 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NEL2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NEL2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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