Protein SPATA31F3 (SPATA31F3)
Homo sapiens — UniProt A6NFA0
Data last refreshed: (UniProt release unknown)
Key facts
Protein SPATA31F3 (SPATA31F3) is a protein from Homo sapiens identified by UniProt accession A6NFA0, 338 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: A6NFA0; gene symbol SPATA31F3.
- Organism: Homo sapiens.
- Length: 338 amino acids.
- Top disease associations (Open Targets): eosinophil count, psoriasis and asthma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein SPATA31F3 |
|---|---|
| UniProt accession | A6NFA0 |
| Gene | SPATA31F3 |
| Organism | Homo sapiens |
| Length | 338 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.25
- psoriasis · score 0.17
- asthma · score 0.10
- allergic disease · score 0.10
- self reported educational attainment · score 0.06
- lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome · score 0.04
- Lung fibrosis - immunodeficiency - 46,XX gonadal dysgenesis · score 0.04
- immunodeficiency 75 · score 0.03
- immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias · score 0.03
- severe combined immunodeficiency due to DCLRE1C deficiency · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NFA0-F1 | alphafold | PREDICTED | 49.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NFA0.
Amino-acid sequence (338 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA31F3?
The strongest Open Targets associations for SPATA31F3 are eosinophil count, psoriasis, asthma, allergic disease and self reported educational attainment.
How long is the SPATA31F3 protein?
The Homo sapiens SPATA31F3 protein (UniProt A6NFA0) is 338 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NFA0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NFA0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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