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Zinc finger protein 316 (ZNF316)

Homo sapiens — UniProt A6NFI3

Gene: ZNF316Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 316 (ZNF316) is a protein from Homo sapiens identified by UniProt accession A6NFI3, 1004 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

  • UniProt accession: A6NFI3; gene symbol ZNF316.
  • Organism: Homo sapiens.
  • Length: 1004 amino acids.
  • Top disease associations (Open Targets): leukocyte count, neutrophil count and sex hormone-binding globulin measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 316
UniProt accessionA6NFI3
GeneZNF316
OrganismHomo sapiens
Length1004 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (17)

Diseases linked to this target (Open Targets).

  • leukocyte count · score 0.29
  • neutrophil count · score 0.27
  • sex hormone-binding globulin measurement · score 0.25
  • myeloid white cell count · score 0.22
  • monocyte count · score 0.16
  • heel bone mineral density · score 0.13
  • IGF-1 measurement · score 0.12
  • vital capacity · score 0.11
  • fasting blood insulin measurement · score 0.04
  • mean corpuscular hemoglobin concentration · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NFI3-F1alphafoldPREDICTED59.70—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NFI3.

Amino-acid sequence (1004 residues)

MAALHTTPDS PAAQLERAED GSECDPDQEE EEEEEEKGEE VQEVEEEEEE IVVEEEEEGV AEVVQDAQVE AVAEVEVEAD VEEEDVKEVL AEEECPALGT QERLSRGGDA KSPVLQEKGL QASRAPATPR DEDLEEEEEE EEDEDEDDLL TAGCQELVTF EDVAVYFSLE EWERLEADQR GLYQEVMQEN YGILVSLGYP IPKPDLIFRL EQGEEPWVPD SPRPEEGDIV TGVYTGAWFW TDDIEDHEEE DDEDFLAEVA EEENEPPGLW SAAYGVGDVP GTWGPDDSDS AQTPEGWGPD PGGLGVLADG SEAKPFLPGR EPGANLLSPW AFPAAVAPPA GRPETTCDVC GKVFPHRSRL AKHQRYHAAV KPFGCEECGK GFVYRSHLAI HQRTHTGEKP FPCPDCGKRF VYKSHLVTHR RIHTGERPYR CAFCGAGFGR RSYLVTHQRT HTGERPYPCS HCGRSFSQSS ALARHQAVHT ADRPHCCPDC GQAFRLRADF QRHRRGGGCA EAGGDGPRRE PGETAAAAGP EDTDPGPEGS EVGEADGEAE AAAEEREEAA VAAPTPSGKV DPAPERRFLE LGNGLGEGEG PSSHPLGFHF PVHPKSWLHP DSFPILGLPD FRERLPVDGR PLPAPLGGPL SLVEGTGLAC DPFGGGGAAG GGGGLRAFGP AIGGLLAEPA PAALAEEESP WICSDCGKTF GRRAALAKHQ RYHAGERPHR CADCGKSFVY GSHLARHRRT HTGERPFPCP ECGARFARGS HLAAHVRGHT GEKPFVCGVC GAGFSRRAHL TAHGRAHTGE RPYACGECGR RFGQSAALTR HQWAHAEEKP HRCPDCGKGF GHSSDFKRHR RTHTGEKPFR CADCGRGFAQ RSNLAKHRRG HTGERPFPCP ECGKRFSQRS VLVTHQRTHT GERPYACANC GRRFSQSSHL LTHMKTHRGA TAAPGSGSAP APAPKPEAAA KGPSSAGPGE RGSALLEFAG GTSFGSEHQA AFAGPSGAYR EGVL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF316?

The strongest Open Targets associations for ZNF316 are leukocyte count, neutrophil count, sex hormone-binding globulin measurement, myeloid white cell count and monocyte count.

How long is the ZNF316 protein?

The Homo sapiens ZNF316 protein (UniProt A6NFI3) is 1004 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NFI3
GeneZNF316
OrganismHomo sapiens
Length1004
Binders0
Diseases17
View on UniProt