Transmembrane protein 191C (TMEM191C)
Homo sapiens — UniProt A6NGB0
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 191C (TMEM191C) is a protein from Homo sapiens identified by UniProt accession A6NGB0, 302 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: A6NGB0; gene symbol TMEM191C.
- Organism: Homo sapiens.
- Length: 302 amino acids.
- Top disease associations (Open Targets): reticulocyte measurement, gut microbiome measurement and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 191C |
|---|---|
| UniProt accession | A6NGB0 |
| Gene | TMEM191C |
| Organism | Homo sapiens |
| Length | 302 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- reticulocyte measurement · score 0.19
- gut microbiome measurement · score 0.17
- mean corpuscular hemoglobin concentration · score 0.15
- Immature Reticulocyte Fraction Measurement · score 0.15
- neurodegenerative disease · score 0.15
- mean corpuscular hemoglobin · score 0.09
- mean corpuscular volume · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NGB0-F1 | alphafold | PREDICTED | 79.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NGB0.
Amino-acid sequence (302 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM191C?
The strongest Open Targets associations for TMEM191C are reticulocyte measurement, gut microbiome measurement, mean corpuscular hemoglobin concentration, Immature Reticulocyte Fraction Measurement and neurodegenerative disease.
How long is the TMEM191C protein?
The Homo sapiens TMEM191C protein (UniProt A6NGB0) is 302 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NGB0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NGB0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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