WAS/WASL-interacting protein family member 3 (WIPF3)
Homo sapiens — UniProt A6NGB9
Data last refreshed: (UniProt release unknown)
Key facts
WAS/WASL-interacting protein family member 3 (WIPF3) is a protein from Homo sapiens identified by UniProt accession A6NGB9, 483 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: A6NGB9; gene symbol WIPF3.
- Organism: Homo sapiens.
- Length: 483 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, urinary albumin to creatinine ratio and Moderate albuminuria.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WAS/WASL-interacting protein family member 3 |
|---|---|
| UniProt accession | A6NGB9 |
| Gene | WIPF3 |
| Organism | Homo sapiens |
| Length | 483 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.47
- urinary albumin to creatinine ratio · score 0.39
- Moderate albuminuria · score 0.29
- albuminuria · score 0.28
- bone quantitative ultrasound measurement · score 0.27
- breast adenocarcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.11
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- partial chromosome Y deletion · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NGB9-F1 | alphafold | PREDICTED | 59.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NGB9.
Amino-acid sequence (483 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WIPF3?
The strongest Open Targets associations for WIPF3 are heel bone mineral density, urinary albumin to creatinine ratio, Moderate albuminuria, albuminuria and bone quantitative ultrasound measurement.
How long is the WIPF3 protein?
The Homo sapiens WIPF3 protein (UniProt A6NGB9) is 483 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NGB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NGB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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