Zinc finger and SCAN domain-containing protein 5C (ZSCAN5C)
Homo sapiens — UniProt A6NGD5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and SCAN domain-containing protein 5C (ZSCAN5C) is a protein from Homo sapiens identified by UniProt accession A6NGD5, 496 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: A6NGD5; gene symbol ZSCAN5C.
- Organism: Homo sapiens.
- Length: 496 amino acids.
- Top disease associations (Open Targets): monocyte count, early-onset non-syndromic cataract and FRAXF syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 5C |
|---|---|
| UniProt accession | A6NGD5 |
| Gene | ZSCAN5C |
| Organism | Homo sapiens |
| Length | 496 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.08
- early-onset non-syndromic cataract · score 0.07
- FRAXF syndrome · score 0.06
- Cataract-microcornea syndrome · score 0.06
- Total congenital cataract · score 0.06
- isolated ectopia lentis · score 0.06
- Cataract with Y-shaped suture opacities · score 0.05
- Anterior polar cataract · score 0.05
- Posterior polar cataract · score 0.05
- cataract · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NGD5-F1 | alphafold | PREDICTED | 58.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NGD5.
Amino-acid sequence (496 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZSCAN5C?
The strongest Open Targets associations for ZSCAN5C are monocyte count, early-onset non-syndromic cataract, FRAXF syndrome, Cataract-microcornea syndrome and Total congenital cataract.
How long is the ZSCAN5C protein?
The Homo sapiens ZSCAN5C protein (UniProt A6NGD5) is 496 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NGD5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NGD5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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