Tripartite motif-containing protein 64 (TRIM64)
Homo sapiens — UniProt A6NGJ6
Data last refreshed: (UniProt release unknown)
Key facts
Tripartite motif-containing protein 64 (TRIM64) is a protein from Homo sapiens identified by UniProt accession A6NGJ6, 449 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: A6NGJ6; gene symbol TRIM64.
- Organism: Homo sapiens.
- Length: 449 amino acids.
- Top disease associations (Open Targets): hair colour measurement, basophil count and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tripartite motif-containing protein 64 |
|---|---|
| UniProt accession | A6NGJ6 |
| Gene | TRIM64 |
| Organism | Homo sapiens |
| Length | 449 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- hair colour measurement · score 0.02
- basophil count · score 0.02
- smoking status measurement · score 0.02
- atherosclerosis · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NGJ6-F1 | alphafold | PREDICTED | 85.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NGJ6.
Amino-acid sequence (449 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIM64?
The strongest Open Targets associations for TRIM64 are hair colour measurement, basophil count, smoking status measurement, atherosclerosis and cancer.
How long is the TRIM64 protein?
The Homo sapiens TRIM64 protein (UniProt A6NGJ6) is 449 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NGJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NGJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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