Speedy protein E2B (SPDYE2B)
Homo sapiens — UniProt A6NHP3
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E2B (SPDYE2B) is a protein from Homo sapiens identified by UniProt accession A6NHP3, 402 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: A6NHP3; gene symbol SPDYE2B.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, chronotype measurement and neuronal ceroid lipofuscinosis 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E2B |
|---|---|
| UniProt accession | A6NHP3 |
| Gene | SPDYE2B |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- chronotype measurement · score 0.04
- neuronal ceroid lipofuscinosis 1 · score 0.03
- insomnia measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NHP3-F1 | alphafold | PREDICTED | 60.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NHP3.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE2B?
The strongest Open Targets associations for SPDYE2B are neurodegenerative disease, chronotype measurement, neuronal ceroid lipofuscinosis 1 and insomnia measurement.
How long is the SPDYE2B protein?
The Homo sapiens SPDYE2B protein (UniProt A6NHP3) is 402 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NHP3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NHP3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.