Leucine-rich repeat-containing protein 10B (LRRC10B)
Homo sapiens — UniProt A6NIK2
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 10B (LRRC10B) is a protein from Homo sapiens identified by UniProt accession A6NIK2, 292 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: A6NIK2; gene symbol LRRC10B.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): hypertension, systolic blood pressure and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 10B |
|---|---|
| UniProt accession | A6NIK2 |
| Gene | LRRC10B |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- hypertension · score 0.34
- systolic blood pressure · score 0.32
- diastolic blood pressure · score 0.32
- mean arterial pressure · score 0.32
- alcohol drinking · score 0.30
- Agents acting on the renin-angiotensin system use measurement · score 0.26
- smoking status measurement · score 0.26
- blood pressure · score 0.21
- Calcium channel blocker use measurement · score 0.20
- cardiovascular disease · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NIK2-F1 | alphafold | PREDICTED | 83.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NIK2.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC10B?
The strongest Open Targets associations for LRRC10B are hypertension, systolic blood pressure, diastolic blood pressure, mean arterial pressure and alcohol drinking.
How long is the LRRC10B protein?
The Homo sapiens LRRC10B protein (UniProt A6NIK2) is 292 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NIK2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NIK2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.