Speedy protein E5 (SPDYE5)
Homo sapiens — UniProt A6NIY4
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E5 (SPDYE5) is a protein from Homo sapiens identified by UniProt accession A6NIY4, 402 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: A6NIY4; gene symbol SPDYE5.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): body mass index, age at first sexual intercourse measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E5 |
|---|---|
| UniProt accession | A6NIY4 |
| Gene | SPDYE5 |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- body mass index · score 0.40
- age at first sexual intercourse measurement · score 0.37
- self reported educational attainment · score 0.33
- systolic blood pressure · score 0.32
- serum alanine aminotransferase measurement · score 0.31
- body fat percentage · score 0.28
- mathematical ability · score 0.27
- lean body mass · score 0.27
- fat body mass · score 0.25
- body weight · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NIY4-F1 | alphafold | PREDICTED | 59.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NIY4.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE5?
The strongest Open Targets associations for SPDYE5 are body mass index, age at first sexual intercourse measurement, self reported educational attainment, systolic blood pressure and serum alanine aminotransferase measurement.
How long is the SPDYE5 protein?
The Homo sapiens SPDYE5 protein (UniProt A6NIY4) is 402 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NIY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NIY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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